Diagnosis of Toxoplasma and Toxocara from the Aqueous Humor

Authors: B. Kostolná ;  A. Gerinec ;  F. Ondriska *
Authors‘ workplace: Klinika detskej oftalmológie LFUK – DFNsP, Bratislava, prednosta prof. MUDr. A. Gerinec, CSc. *HPL s. r. o., Bratislava, riaditeľ MUDr. J. Hanzen
Published in: Čes. a slov. Oftal., , 2003, No. 5, p. 312-318


The authors discuss methods of improvement of the etiologic diagnosis of thetoxoplasma and toxocara associated posterior uveititis, by examining specificantibodies in the aqueous humor. Paired samples of aqueous humor and serumwere analyzed in 23 patients. Chorioretinitis of infectious etiology was suspectedin 15 patients, 3 patients were treated for panuveitis, 4 patients for intermediateuveitis, and in 1 patient the sample was obtained to rule out malignant melanoma.The local ocular antibody production was calculated according to Desmonts.Toxoplasma etiology was confirmed by local antibody production analysis in 1patient, toxocara etiology in 5 patients. In 20 patients in the control group localspecific antibody production was not demonstrated.

Key words:
Toxoplasma gondii, Toxocara canis, aqueous humor, specific antibodies,diagnosis of charioretinitis

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