Fixed-dose combinations of antidiabetic drugs

Authors: M. Paclíková;  A. Šmahelová
Authors‘ workplace: Diabetologické centrum, III. interní geronto-metabolická klinika LF UK a FN Hradec Králové
Published in: Kardiol Rev Int Med 2016, 18(2): 104-108


Current guidelines from ADA (American Diabetes Association) and EASD (European Association for the Study of Diabetes) for the treatment of type 2 diabetes, underline individualisation of treatment, early start of combination therapy to hit more pathophysiological pathways, and consistent treatment of comorbidities. The fixed combinations of antidiabetic drugs provide good means to achieving these goals without increasing the number of tablets. This article presents an overview of the currently available fixed combinations of antidiabetic drugs, their importance in the treatment of type 2 diabetes, and considers the importance and the possibilities of influencing patients' adherence to treatment.

type 2 diabetes mellitus –  combination therapy –  fixed-dose combination –  adherence to the treatment


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