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Basic Cardiovascular Benefits of the Oral Antidiabetic Medication Empagliflozin

18. 11. 2021 Source: Heart Failure

Type 2 diabetes mellitus is one of the main risk factors for cardiovascular (CV) diseases. Empagliflozin is among the modern oral antidiabetic medications, and in 2015 it became a pioneer among diabetes treatments shown to reduce the incidence of major CV events. It has also been proven to reduce the risk of hospitalization for heart failure.

Operace_operačnísál_lékaři

Reversal of Dabigatran Effects with Idarucizumab in Patients Requiring Urgent Procedures: Subanalysis of the RE-VERSE AD Study

The effect of idarucizumab as a reversal agent in patients treated with dabigatran in situations requiring urgent surgery or other invasive procedures was evaluated in a subanalysis from the RE-VERSE…
18. 11. 2021 Source: Anticoagulant Treatment
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Safety of Dabigatran According to a Meta-Analysis of 7 Randomized Controlled Trials

Dabigatran is a direct thrombin inhibitor from the group of direct oral anticoagulants (DOACs), developed as an alternative to vitamin K antagonists. The aim of the recently published meta-analysis…
18. 11. 2021 Source: Anticoagulant Treatment
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Efficacy and Safety of Dual Bronchodilator Therapy for COPD –⁠ From Randomized Clinical Trials to Real-World Clinical Practice

Dual bronchodilator therapy (LAMA + LABA) represents one of the mainstays of treating chronic obstructive pulmonary disease (COPD). The aim of the recent systematic review presented below was to…
18. 11. 2021 Source: Treatment of Asthma and COPD
kapka krve cukr srdce cukrovka diabetes srdeční

Epidemiology, Pathophysiology, Diagnosis, and Treatment of Heart Failure in Patients with Diabetes

The proven benefit of one class of antidiabetic drugs –⁠ sodium-glucose cotransporter 2 inhibitors (SGLT2i; gliflozins) –⁠ in treating heart failure irrespective of diabetes presence, and their…
18. 11. 2021 Source: Cardiovascular Continuum
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Subclinical Hypothyroidism Associated with the Use of Allopurinol? What the Results of a Large Multicenter Study Suggested

Allopurinol is a widely used drug for the treatment of hyperuricemia and gout. The retrospective study presented below investigated whether its long-term use is associated with an increased risk of…
18. 11. 2021 Source: Thyroid Disorders

Does the emergence of resistance to cetuximab mean ineffectiveness of all anti-EGFR antibodies?

Colorectal cancer (CRC) cells respond to targeted therapy in different ways. Besides the desired outcome of cell death, CRC cells can adapt and survive through changes in their genome. It is…
12. 11. 2021 Source: Colorectal Cancer
ATB léčba infekcí vyvolaných MDR bakteriemi /Webinář 2.11.2021

VIDEO: Antibiotic Treatment of Infections Caused by MDR Bacteria –⁠ Seminar Recording

Recording of a professional seminar on the topic of infections caused by MDR bacteria, which took place on November 2, 2021, at the Medical House in Prague.
11. 11. 2021 Source: Anti-Infectives
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Genetic Profiling Transforms the Diagnosis and Treatment of Cancer Diseases

Genome sequencing provides doctors with more information about the causes of cancer diseases and changes the ways of treating tumors. Targeted therapy aimed at oncogenic mutations has brought…
11. 11. 2021 Source: Genetic Profile and Treatment of NSCLC
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Dosing of Enoxaparin in Morbidly Obese Patients

How to optimally dose enoxaparin in morbidly obese patients? This question was addressed by a randomized study, the results of which were published in the journal Annals of Pharmacotherapy.
11. 11. 2021 Source: Thromboprophylaxis
Psoriaza_loket_pacient_lékař

Is long-term treatment with ixekizumab sufficiently safe?

Psoriasis is a chronic inflammatory disease whose manifestations require long-term treatment. A poster presented at last year's European Academy of Dermatology and Venereology (EADV) congress…
8. 11. 2021 Source: Biological Treatment
astma plíce chopn grafika novinka

Do Asthma Bronchiale and COPD Represent a Risk Factor for Severe COVID-19 and Death?

It is well known that patients with bronchial asthma and chronic obstructive pulmonary disease (COPD) have a higher risk of severe course of common viral respiratory diseases. A study by Belgian…
8. 11. 2021 Source: Treatment of Asthma and COPD
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Risk Factors for Renal Cancer Formation After Kidney Transplantation

German authors in the below-cited work identified modifiable risk factors associated with the development of renal cell carcinoma (RCC) de novo in patients after kidney transplantation.
5. 11. 2021 Source: Kidney Carcinoma
Ledvina_karcinom

Kidney Carcinoma –⁠ Key Facts About the Disease With the Highest Incidence Worldwide in the Czech Republic

The incidence of renal carcinoma is increasing every year. About a quarter of the cases are still diagnosed in the metastatic stage, yet early treatment can save lives. Below, we briefly summarize…
5. 11. 2021 Source: Kidney Carcinoma
Mladý mužský pacient na návštěvě ženského lékaře traumatologa

Clinical Characteristics of Trauma Patients Requiring Dosing Adjustments of Enoxaparin in TEN Prevention

Injuries and trauma surgical procedures represent a significant risk factor for the development of thromboembolic disease (TEN). Routine thromboprophylaxis is thus recommended for trauma patients,…
4. 11. 2021 Source: Thromboprophylaxis
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