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Summary of New American Recommendations for Heart Failure Management
This year, the American Heart Association (AHA), the American College of Cardiology (ACC), and the Heart Failure Society of America (HFSA) released joint recommendations for the diagnosis and treatment of heart failure in clinical practice. These new guidelines replace the previous recommendations from 2013 and their 2017 update. We summarize the 10 key points to remember as outlined by the authors of the new guidelines and focus on the treatment of the subgroup of patients with heart failure with preserved ejection fraction (HFpEF).

Full Compensation of Seizures as the Main Goal of Epilepsy Therapy: Will Patients Achieve It More Easily Than 20 Years Ago?
What is the relationship between the quality of life of patients and the degree of seizure…

Safety Profile of Metamizole – A Systematic Review
Metamizole is a long-established non-steroidal analgesic used for acute and chronic pain…

Early and effective treatment of PBC significantly reduced the need for liver transplantation due to this disease
Current European and Czech guidelines include obeticholic acid (OCA) as the only registered option…

Iron Deficiency and Administration of Ferric Carboxymaltose in Patients with Heart Failure
Iron deficiency is very common in patients with heart failure and is associated with exercise…

Does empagliflozin improve the overall health of patients with heart failure with reduced LVEF?
A recently published secondary analysis of the EMPEROR-Reduced study is based mainly on the results…

Comparison of Dabigatran and Vitamin K Antagonists in Patients with Atrial Fibrillation in Real-World Practice
The final 3-year results of the GLORIA-AF study conducted in real-world practice with patients…

Low-Molecular-Weight Heparins in Thromboprophylaxis After Major Orthopedic and Traumatological Procedures According to Current Recommendations
Patients after major orthopedic and traumatological procedures are at high risk of thromboembolic disease....

Successful Resection of a Rectosigmoid Tumor After Long-term Induction Biochemotherapy – A Case Report
Neoadjuvant treatment (chemoradiotherapy) for colorectal cancer is regularly used in advanced…

Dupilumab Improves Skin and Systemic Symptoms of Atopic Dermatitis
A clinical study conducted in the USA and Canada demonstrated the efficacy of dupilumab in treating…
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