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Early Intervention in the Early Phase of Psychosis

27. 10. 2021 Source: Modern Treatment of Schizophrenia

A meta-analysis of 10 randomized studies examined whether early intervention in the initial phase of psychosis in patients with schizophrenia is associated with better outcomes than usual care.

Association between Cardiovascular Risk Factors and Cognitive Disorders in Patients with Schizophrenia

Schizophrenia is a disease characterized by a certain degree of cognitive impairment, but also an increased risk of cardiovascular diseases, which are often the cause of deteriorating cognitive…

27. 10. 2021 Source: Modern Treatment of Schizophrenia

žena postel polštář peřina spánek únava deprese

How Do Sleep and Depression Influence Each Other?

It is known that most patients with depression encounter some form of sleep disorder. In the following text, we briefly explore the complex relationship between depression and sleep and offer some…

27. 10. 2021 Source: Depression and Anxiety

Conditions for the Use of Mucolytics in Children Are Tightening in Europe −⁠ Which Treatment Is Preferred?

There has been a long-standing discussion among experts regarding the benefits of individual mucomodulatory drugs in the treatment of productive cough in children. According to current…

25. 10. 2021 Source: Cough Therapy

Optimization of Romiplostim Administration in ITP Treatment

In their newly published review article, authors from several American institutions summarize findings on the role of romiplostim in the treatment of immune thrombocytopenia (ITP) and its efficacy…

22. 10. 2021 Source: Immune Thrombocytopenia

Fatigue as a Significant Symptom of Immune Thrombocytopenia from the Patients' Perspective

The I-WISh survey assessed the impact of immune thrombocytopenia (ITP) and its treatment on patients' lives. Patients identified fatigue as the most frequent, severe, and persistent symptom…

22. 10. 2021 Source: Immune Thrombocytopenia

Final Analysis of the STASEY Study: How Did Emicizumab Fare in the Prophylaxis of Hemophilia A Patients with FVIII Inhibitors?

The July virtual congress of the International Society on Thrombosis and Haemostasis (ISTH) 2021 offered a variety of interesting topics. Among the poster presentations, data from the multicenter, single-arm,...

21. 10. 2021 Source: Rare Diseases in Hematology

Mucormycosis Associated with COVID-19 –⁠ Case Report and Review of Current Knowledge

Systemic corticosteroids are among the treatments used for patients with severe COVID-19. These patients are at increased risk of opportunistic bacterial and fungal infections. Pulmonary aspergillosis...

20. 10. 2021 Source: Anti-Infectives

Alemtuzumab –⁠ Does Age Matter? Or Not?

The authors of a study published this year focused on the safety and efficacy of alemtuzumab in patients with relapsing-remitting multiple sclerosis (RRMS). How did it perform over the observed…

18. 10. 2021 Source: Multiple Sclerosis

Does Teriflunomide Bloom at Every Age?

What impact does age have on the effectiveness of multiple sclerosis (MS) therapy in real-world clinical practice? How do the outcomes differ for patients treated with teriflunomide considering their…

18. 10. 2021 Source: Multiple Sclerosis

How Does Memantine Currently Stand in Alzheimer's Disease and Other Dementias

A comprehensive meta-analysis from 2019 examined the effect and safety of administering memantine, particularly in patients with moderate to severe Alzheimer's disease. How did memantine fare?

17. 10. 2021 Source: Cognitive in the treatment of Alzheimer's disease

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Treatment of Metastatic Colorectal Cancer During the COVID-19 Pandemic

In the conditions of the coronavirus pandemic, it is difficult to maintain good accessibility to ongoing comprehensive oncological care, and thus the quality of life of patients. An international…

15. 10. 2021 Source: Treatment of Gastrointestinal Carcinomas

Biosimilar MB02 as an Alternative to Bevacizumab in Lung Cancer Treatment

The STELLA clinical trial aimed to evaluate the efficacy, safety, and immunogenicity of MB02, a biosimilar to bevacizumab, in patients with advanced non-small cell lung cancer.

15. 10. 2021 Source: Oncological Treatment

Efficacy and Safety of Gefitinib in Combination with Chemotherapy vs. Chemotherapy Alone in the Treatment of Advanced NSCLC

Non-small cell lung cancer (NSCLC) remains a disease with high mortality. The meta-analysis presented below compared the efficacy and safety of gefitinib in combination with chemotherapy versus…

15. 10. 2021 Source: Oncological Treatment

Nasal Smear as a Modern and Gentle Diagnostic Method for Allergic Rhinitis

Up to 130 million Europeans suffer from allergic rhinitis. Until now, standard diagnostic methods have been skin prick tests and laboratory blood tests. Both methods, however, present significant…

14. 10. 2021 Source: Allergic Reactions

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