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Cost-Effectiveness of Preparations Used to Stop Bleeding in Patients with AHA

1. 11. 2021 Source: Hemophilia

Choosing the right preparation to manage acute bleeding in patients with acquired hemophilia A is not always simple. An interesting perspective and recommendations are provided by a model analysis assessing the cost and effectiveness of individual available preparations.

Risk of Developing Inhibitors in People with Milder Forms of Hemophilia

Moderate and mild hemophilia A differ from the severe form not only in clinical course and bleeding risk, but also in the risk of developing neutralizing antibodies (inhibitors).

1. 11. 2021 Source: Hemophilia

Screening using NGS in patients with metastatic NSCLC –⁠ initial results from the ALK-positive cohort

Next-generation sequencing (NGS) allows for obtaining a large amount of information about the tumor genome from a patient's blood sample. Currently, the method is recommended as an alternative in…

1. 11. 2021 Source: Genetic Profile and Treatment of NSCLC

Efficacy and Safety of Dupilumab in the Treatment of Atopic Dermatitis in Adolescents

In the pediatric population, atopic dermatitis (AD) has a relatively high prevalence, but therapeutic options are often limited. The following article offers a summary of the results from a clinical…

1. 11. 2021 Source: Systemic treatment of atopic dermatitis, asthma, and chronic rhinosinusitis with nasal polyposis – Type 2 inflammation

Quick Relief from Severe AD Symptoms –⁠ Dupilumab for Children Aged 6 Years and Older

Children aged 6-12 with severe atopic dermatitis (AD) have very limited treatment options. The studies presented below demonstrate how effective and safe dupilumab, a monoclonal antibody targeting…

1. 11. 2021 Source: Systemic treatment of atopic dermatitis, asthma, and chronic rhinosinusitis with nasal polyposis – Type 2 inflammation

Probiotic L. reuteri in combination with vitamin D3 and krill oil suppresses experimental intestinal inflammation

Previous placebo-controlled studies have shown that oral administration of a probiotic containing Lactobacillus reuteri is associated with a significant increase in plasma levels of 25-hydroxyvitamin...

29. 10. 2021 Source: GI, colic and microbiome

Dust Mite Allergy and the Risk of Sleep-Disordered Breathing

New York authors in their recently published retrospective analysis tested the hypothesis that individuals with allergic rhinitis caused by dust mite allergy have an increased risk of breathing disorders...

29. 10. 2021 Source: Dust Mite Allergy

Effect of Empagliflozin on Clinical Stability in Patients with Heart Failure and Reduced LV Ejection Fraction

Previous studies have shown that the oral antidiabetic drug empagliflozin reduces the risk of death from cardiovascular causes or hospitalization for heart failure in patients with heart failure with…

29. 10. 2021 Source: Diabetes

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Overlap of SGLT2 Inhibitors from Diabetology to Cardiology

As recent research shows, one of the modern groups of antidiabetic drugs -⁠ SGLT2 inhibitors, also known as gliflozins -⁠ brings benefits not only in diabetology but also in cardiology and nephrology.…

29. 10. 2021 Source: Diabetes

Heart Failure in the Light of New ESC Guidelines

Dear Doctor, The Czech Society of Internal Medicine of ČLS JEP invites you to watch the symposium, which will take place on Wednesday, November 3rd, at 5 PM.
You can find more information in the…

27. 10. 2021 Source: Heart Failure

Heart Failure in Light of New ESC Guidelines

Dear Doctor, The Czech Society of Internal Medicine ČLS JEP invites you to watch the symposium, which will take place on Wednesday, November 3rd at 5 PM.
You can find more information in the attached…

27. 10. 2021 Source: Anticoagulant Treatment

Early Intervention in the Early Phase of Psychosis

A meta-analysis of 10 randomized studies examined whether early intervention in the initial phase of psychosis in patients with schizophrenia is associated with better outcomes than usual care.

27. 10. 2021 Source: Modern Treatment of Schizophrenia

Association between Cardiovascular Risk Factors and Cognitive Disorders in Patients with Schizophrenia

Schizophrenia is a disease characterized by a certain degree of cognitive impairment, but also an increased risk of cardiovascular diseases, which are often the cause of deteriorating cognitive…

27. 10. 2021 Source: Modern Treatment of Schizophrenia

žena postel polštář peřina spánek únava deprese

How Do Sleep and Depression Influence Each Other?

It is known that most patients with depression encounter some form of sleep disorder. In the following text, we briefly explore the complex relationship between depression and sleep and offer some…

27. 10. 2021 Source: Depression and Anxiety

Conditions for the Use of Mucolytics in Children Are Tightening in Europe −⁠ Which Treatment Is Preferred?

There has been a long-standing discussion among experts regarding the benefits of individual mucomodulatory drugs in the treatment of productive cough in children. According to current…

25. 10. 2021 Source: Cough Therapy

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