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Brigatinib in the Therapy of ALK-Positive NSCLC in Patients Refractory to Crizotinib Therapy – Results of the Final Analysis of Clinical Studies

9. 9. 2021 Source: Non-Small Cell Lung Cancer

Previously published results of clinical studies have shown that in patients refractory to crizotinib therapy, the administration of brigatinib led to a high rate of therapeutic response (systemic and intracranial) and simultaneously improved median progression-free survival. Additional results presented at this year's ASCO congress included the final outcomes of studies focusing on the administration of brigatinib specifically in patients refractory to crizotinib therapy.

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Brigatinib in the Therapy of ALK-Positive NSCLC – First Results of the J-ALTA Study

Brigatinib is an anaplastic lymphoma kinase (ALK) inhibitor with broad and potent activity against…
9. 9. 2021 Source: Non-Small Cell Lung Cancer
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Ivabradine and/or Sacubitril/Valsartan in the Treatment of Heart Failure with Reduced Ejection Fraction

Ivabradine and sacubitril/valsartan are used in the second line of therapy for heart failure with…
7. 9. 2021 Source: Chronic Heart Failure and Lipidology
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Variability of COPD Symptoms During the Day and Impact on Patients' Morning Routine – Survey Results

Chronic obstructive pulmonary disease (COPD) is viewed, unlike bronchial asthma, as a condition…
7. 9. 2021 Source: COPD
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Atectura® and Enerzair® from May 1, 2021 with Health Insurance Coverage

The fixed combination of indacaterol acetate (LABA) and mometasone furoate (ICS) Atectura® and the…
2. 9. 2021 Source: Asthma under control
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New Strategies in the Treatment of Schizophrenia

Schizophrenia was primarily associated with dopamine dysfunction. Previous and current treatments…
30. 8. 2021 Source: Schizophrenia and Antipsychotics
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Is it safe to start dabigatran in the first days after ischemic stroke?

For patients after cardioembolic ischemic stroke (iCMP), starting anticoagulant therapy is crucial,…
27. 8. 2021 Source: Anticoagulant Treatment
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Is the combination of tiotropium/olodaterol proven more effective in reducing the risk of clinically significant worsening of COPD compared to monotherapy?

Given the heterogeneity of chronic obstructive pulmonary disease (COPD), the use of a composite…
26. 8. 2021 Source: COPD
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Impact of Chronic Urticaria on Patients' Quality of Life and Society

An international team of dermatologists has mapped out the impact of chronic urticaria on various…
25. 8. 2021 Source: Allergic Reactions
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Perioperative substitution therapy in patients with vWD must be tailored

Even in cases of von Willebrand disease (vWD), available data supports the need for individualized…
25. 8. 2021 Source: Von Willebrand Disease
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