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KDIGO: The Choice of Dialysis Modality Must Consider Patient Individuality

27. 5. 2020 Source: Chronic Kidney Disease

The moment of initiating dialysis, as well as the period immediately before and after it, is crucial for good treatment outcomes. But what exactly can be considered a good outcome, and do the perspectives of doctors and patients align on this issue? Leading nephrologists worldwide discussed this at the KDIGO conference, which was specifically focused on controversies in dialysis treatment.

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Perioperative Management in Patients with Atrial Fibrillation Treated with NOACs

The recommended procedures for perioperative management in patients using novel oral anticoagulants (NOACs) stem from the requirement to minimize treatment interruption before and after surgical…
27. 5. 2020 Source: Anticoagulant Treatment
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Obstacle Called Vasospasm: Which Solution Is Most Effective in Microsurgery and How to Pharmacologically Assist It?

Turkish authors in their study focused on the use of metamizole in addressing vasospasm in microsurgery. Using an animal model, they sought to answer the question of how this drug compares to…
27. 5. 2020 Source: Analgesia
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Cannabidiol as a way to reduce anxiety in patients with Parkinson's disease?

A recent study by Brazilian authors examined the effects of cannabidiol on tremors and anxiety in patients with Parkinson's disease. Could it represent a promising modality in this indication?
27. 5. 2020 Source:
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Thromboprophylaxis in Cancer Patients −⁠ Results of Current Meta-Analysis

A recently published meta-analysis shows the benefits of thromboprophylaxis in cancer patients, with no increased risk of severe bleeding complications.
27. 5. 2020 Source: Thromboprophylaxis
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About Sartans: An Overview with Consideration of Their Position in the Current Coronavirus Situation

Sartans, or AT1 receptor blockers for angiotensin II (ARBs), are among the first-line antihypertensives, along with angiotensin-converting enzyme inhibitors (ACEi). These are well-tested drugs with a…
26. 5. 2020 Source: Sartans in the Treatment of Hypertension

Modern Techniques and MRI Markers in Multiple Sclerosis Imaging or How to Increase Specificity and Sensitivity of Examinations

MRI is a key component in the diagnosis of multiple sclerosis (MS). However, despite significant progress in imaging methods, specificity is still not optimal. The current trend is to refine and…
26. 5. 2020 Source: Multiple Sclerosis
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Combination of Candesartan with ACE Inhibitors in the Treatment of Hypertension and Heart Failure

Although the combination of ACE inhibitors and sartans is not recommended due to the higher incidence of complications, studies also indicate a positive effect of their concurrent administration. The…
25. 5. 2020 Source: Sartans in the Treatment of Hypertension
srdce lékař medicína

Development of Albuminuria During Treatment with ACE Inhibitors and Sartans

Individual molecules from the class of renin-angiotensin system inhibitors display various distinct properties at the molecular level, and their renoprotective potential may differ. A study by Korean…
25. 5. 2020 Source: Sartans in the Treatment of Hypertension

Targeted DNA Sequencing Helps Find Targeted Therapy for Patients with NSCLC

Gene sequencing has become a key tool in deciding the treatment for patients with non-small cell lung cancer (NSCLC). At a university in Seoul, South Korea, a retrospective analysis of the benefits…
25. 5. 2020 Source: Genetic Profile and Treatment of NSCLC
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Hypnotics in the Therapy of Insomnia (Not Only) in the Elderly

Problems with insomnia make up a significant part of the subjective complaints, especially of older patients in our clinics. Up to 1/3 of the population may suffer from chronic insomnia symptoms, and…
25. 5. 2020 Source: Geriatric Patient
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Safety and efficacy of dabigatran and other NOACs compared with warfarin in patients with atrial fibrillation –⁠ results of a large long-term prospective study

Anticoagulant therapy is key in the prevention of strokes in patients with atrial fibrillation. Until the introduction of new oral anticoagulants (NOACs), warfarin was the first-choice drug for these…
25. 5. 2020 Source: Anticoagulant Treatment
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Primum non nocere applies not only in medicine: an ecological look at inhalers

According to estimates from the World Health Organization (WHO), around 65 million people worldwide suffer from mild to moderate forms of chronic obstructive pulmonary disease (COPD). The cornerstone…
25. 5. 2020 Source: COPD
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Effect of Beta-Blockers on Glucose Metabolism and Their Use in Diabetics with Hypoglycemic Episodes

Beta-blockers, through their mechanism of action, can lead to the deepening or direct initiation of both hypoglycemia and hyperglycemia. The study presented below, published last year, evaluated the…
21. 5. 2020 Source: Cardiovascular Continuum
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Trazodone with Extended Release Improves Patient Compliance

Since 2015, the antidepressant trazodone is available in the Czech Republic in a controlled-release formulation. A sufficiently high plasma level for 24 hours without fluctuation allows for…
20. 5. 2020 Source: Depression and Anxiety
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