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When Size Matters or What Is Small Is Effective

28. 5. 2020 Source: Venous Insufficiency

The systemic effect of an orally administered drug can be expected, among other things, if it has suitable physicochemical properties. How can insufficient absorption or poor solubility be solved? We provide the answer below.

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Diosmin Succeeded in Preventing Ovarian Hyperstimulation Syndrome in Study

In a recently published study, diosmin was evaluated in women undergoing in vitro fertilization (IVF). Attention was focused on its effect in preventing and treating ovarian hyperstimulation syndrome…

28. 5. 2020 Source: Venous Insufficiency

Study COPDGene Redefines Diagnostic Criteria of Chronic Obstructive Pulmonary Disease

Chronic obstructive pulmonary disease ranks among the top causes of morbidity and mortality worldwide. Current diagnostic criteria for the disease are based exclusively on spirometric examination.…

28. 5. 2020 Source: COPD

Preserving Quality of Life for Patients During Palliative Treatment of Triple-Negative Breast Cancer

An analysis of the quality of life of patients treated with a combination of atezolizumab with nab-paclitaxel for metastatic triple-negative breast cancer was published in the Annals of Oncology…

28. 5. 2020 Source: Breast Carcinoma

Quality of Life of Patients on Adjuvant Treatment for HER2-Positive Breast Cancer

The KATHERINE clinical trial demonstrated that adjuvant therapy with trastuzumab emtansine compared to trastuzumab significantly improves invasive disease-free survival in patients with HER2-positive…

28. 5. 2020 Source: Breast Carcinoma

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High Dose of Protein Affects Mortality in Critically Ill Patients if They Do Not Have Sepsis

The optimal composition of nutrition in terms of adequate energy and protein intake for critically ill patients is still a subject of professional discussion. The study cited below aimed to shed more…

28. 5. 2020 Source: Parenteral Nutrition

KDIGO: The Choice of Dialysis Modality Must Consider Patient Individuality

The moment of initiating dialysis, as well as the period immediately before and after it, is crucial for good treatment outcomes. But what exactly can be considered a good outcome, and do the…

27. 5. 2020 Source: Chronic Kidney Disease

Perioperative Management in Patients with Atrial Fibrillation Treated with NOACs

The recommended procedures for perioperative management in patients using novel oral anticoagulants (NOACs) stem from the requirement to minimize treatment interruption before and after surgical…

27. 5. 2020 Source: Anticoagulant Treatment

Obstacle Called Vasospasm: Which Solution Is Most Effective in Microsurgery and How to Pharmacologically Assist It?

Turkish authors in their study focused on the use of metamizole in addressing vasospasm in microsurgery. Using an animal model, they sought to answer the question of how this drug compares to…

27. 5. 2020 Source: Analgesia

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Cannabidiol as a way to reduce anxiety in patients with Parkinson's disease?

A recent study by Brazilian authors examined the effects of cannabidiol on tremors and anxiety in patients with Parkinson's disease. Could it represent a promising modality in this indication?

27. 5. 2020 Source:

Thromboprophylaxis in Cancer Patients −⁠ Results of Current Meta-Analysis

A recently published meta-analysis shows the benefits of thromboprophylaxis in cancer patients, with no increased risk of severe bleeding complications.

27. 5. 2020 Source: Thromboprophylaxis

About Sartans: An Overview with Consideration of Their Position in the Current Coronavirus Situation

Sartans, or AT1 receptor blockers for angiotensin II (ARBs), are among the first-line antihypertensives, along with angiotensin-converting enzyme inhibitors (ACEi). These are well-tested drugs with a…

26. 5. 2020 Source: Sartans in the Treatment of Hypertension

Modern Techniques and MRI Markers in Multiple Sclerosis Imaging or How to Increase Specificity and Sensitivity of Examinations

MRI is a key component in the diagnosis of multiple sclerosis (MS). However, despite significant progress in imaging methods, specificity is still not optimal. The current trend is to refine and…

26. 5. 2020 Source: Multiple Sclerosis

Combination of Candesartan with ACE Inhibitors in the Treatment of Hypertension and Heart Failure

Although the combination of ACE inhibitors and sartans is not recommended due to the higher incidence of complications, studies also indicate a positive effect of their concurrent administration. The…

25. 5. 2020 Source: Sartans in the Treatment of Hypertension

Development of Albuminuria During Treatment with ACE Inhibitors and Sartans

Individual molecules from the class of renin-angiotensin system inhibitors display various distinct properties at the molecular level, and their renoprotective potential may differ. A study by Korean…

25. 5. 2020 Source: Sartans in the Treatment of Hypertension

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