L. Škárka; B. Ošťádal
Centrum experimentálního výzkumu chorob srdce a cév, Fyziologický ústav Akademie věd České republiky, Praha
Čas. Lék. čes. 2004; : 809-816
Besides their traditional role as the energy factory of the cell, mitochondria play an important role in other aspectsof cardiac cell functioning under physiological and pathological conditions. They are involved in the regulation ofcalcium homeostasis, production of reactive oxygen species as well as in the process of cardiac cell death. Recently,the interest in their participation in ischemia-reperfusion injury and potential role in cardioprotective mechanisms,with particular attention to developmental aspects has markedly increased.