Microalbuminuria. From diabetes to cardiovascular risk

Authors: V. Monhart 1,2
Authors‘ workplace: Interní klinika 1. lékařké fakulty UK a ÚVN Praha, přdnosta prof. MUDr. Miroslav Zavoral, Ph. D. 1;  Nefrologická ambulance Synlab Czech s. r. o. Praha 2
Published in: Vnitř Lék 2011; 57(3): 293-298
Category: 60th birthday of prof. Mudr. Jiřího Vítovce, CSc, FESC


An increased albuminuria level, known as microalbuminuria is associated with a range of diseases, most frequently with diabetes mellitus and hypertension. Microalbuminuria in type 1 diabetes is an early sign of diabetic nephropathy onset, while it tends to be an indicator of the level of cardiovascular risk in type 2 diabetes and essential hypertension. At present, an increased albumin excretion is considered to be a renal symptom of generalized endothelial dysfunction. A simple investigation, not bothersome to a patient, should be performed early and repeatedly in all patients with diabetes and hypertension, as low microalbuminaemia levels can be managed with appropriate treatment.

Key words:
microalbuminuria – diabetes mellitus – hypertension – endothelial dysfunction – cardiovascular risk


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