Nifedipine with Controlled Release in Monotherapy of Hypertension

Authors: L. Oral;  J. Juchelka;  G. Ožanová;  D. Stejskal
Authors‘ workplace: Interní oddělení Nemocnice Šternberk přednosta MUDr. I. Oral, CSc.
Published in: Prakt. Lék. 2002; (10): 614-617


The authors treated a group of 30 patients with mild hypertension checking the causal BP and using 24-bour ambulatory monitoring of the blond pressure for a 4-week period with nifedipine as monotherapy.They proved a significant drop of values of the causal systolic and diastolic blond pressure as well as a drop of the mean and individual pressure readings during 24-bour ambulatory monitoring of the blond pressure. The drop of pressure readings was associated with the proved drop of peripheral vascular rezistence. The authors did not prove a secondary rise of the cardiac output.The pressure curve during treatment with nifedipine imitated the physiological circadian blond pressure rhythm.Cordipin XL - nifedipine with controlled release is a suitable and safe preparation in the treatment of hypertension.

Key words:
hypertension - calcium channel blockers - nifedipin XL.

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