Plants in the therapy of inflammatory bowel disease


Authors: Z. Vochyánová;  K. Sikorová;  K. Šmejkal;  J. Hošek
Authors‘ workplace: Ústav přírodních léčiv, Farmaceutická fakulta, Veterinární a farmaceutická univerzita Brno
Published in: Gastroent Hepatol 2014; 68(3): 248-254
Category: IBD: Review Article

Overview

Medicinal plants have been used to treat various diseases for thousands of years. Although their popularity has changed in the course of history, the interest in plants and in their active compounds is currently increasing. Today’s research focuses on determining the active substances responsible for the effect and their mechanism of action. Plants have also their place in complementary therapy of chronic inflammatory diseases. Inflammatory bowel disease (IBD), such as Crohn’s disease and ulcerative colitis, are chronic diseases of the gastrointestinal tract. Their incidence has been increasing in recent years and it is difficult to predict the progression of the disease. Due to the unclear aetiology of inflammatory bowel disease, current therapy is not completely successful. Complementary and alternative medicine is widely used by patients because of frequent side effects and lack of effectiveness of the standard therapy. Plant products may provide an alternative or supplementary treatment option to patients. This review brings a survey of plants and their content compounds used in complementary therapy of inflammatory bowel disease with special relevance to clinical studies.

Key words:
experimental animal models – phytotherapy – inflammatory bowel disease – clinical trials

The authors declare they have no potential conflicts of interest concerning drugs, products, or services used in the study.

The Editorial Board declares that the manuscript met the ICMJE „uniform requirements“ for biomedical papers.

Submitted:
5. 2. 2014

Accepted:
31. 3. 2014


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