Experimental electrogastrography


Authors: J. Bureš 1;  I. Tachecí 1;  J. Květina 1;  M. Pavlík 2;  M. Kuneš 3;  K. Musílek 3;  D. Jun 3;  J. Žďárová Karasová 3;  T. Douda 1;  S. Rejchrt 1;  K. Kuča 3;  M. Kopáčová 1
Authors‘ workplace: II. interní gastroenterologická klinika LF UK a FN Hradec Králové 1;  Centrum pokročilých studií, Fakulta vojenského zdravotnictví, Univerzita obrany, Hradec Králové 2;  Centrum biomedicínského výzkumu, FN Hradec Králové 3
Published in: Gastroent Hepatol 2014; 68(3): 237-242
Category: Important Anniversary: Original Article

Práce je věnována památce prof. MUDr. Zdeňka Mařatky, DrSc. u příležitosti 100. výročí jeho narození.

Overview

Surface electrogastrography (EGG) is a non-invasive method of recording gastric myoelectrical activity from cuta­neous leads placed over the stomach. Our group set up and worked out the methods for EGG in experimental pigs. The dominant frequency in pigs is fully comparable with that found in humans. EGG in experimental pigs is feasible. Experimental EGG is an important basis for further preclinical projects in pharmacology and toxicology.

Key words:
electrogastrography – experimental pig – preclinical studies – Sus scrofa f. domestica

The authors declare they have no potential conflicts of interest concerning drugs, products, or services used in the study.

The Editorial Board declares that the manuscript met the ICMJE „uniform requirements“ for biomedical papers.

Submitted:
16. 5. 2014

Accepted:
6. 6. 2014


Sources

1. Fixa B. Happy ninetieth to Professor Zdeněk Mařatka, M.D., D.Sc. Folia Gastroenterol Hepatol 2004; 2(2): 59–61.

2. Mařatka Z. The role of intestinal bacterial flora in the pathogenesis of inflammatory bowel diseases. A two-component hypothesis. Folia Gastroenterol Hepatol 2003; 1(1): 6–11.

3. Chen JZ, McCallum RW (eds). Electrogastrography: principles and applications. New York: Raven Press 1994.

4. Parkman HP, Hasler WL, Barnett JL et al. Electrogastrography: a document prepared by the gastric section of the American Motility Society Clinical GI Motility Test­ing Task Force. Neurogastroenterol Motil 2003; 15(2): 89–102.

5. Koch KL, Stern RM. Handbook of electrogastrography. Oxford: Oxford University Press 2004.

6. Yin J, Chen JD. Electrogastrography: methodology, validation and applica­tions. J Neurogastroenterol Motil 2013; 19(1): 5–17. doi: 10.5056/jnm.2013.19.1.5.

7. Murakami H, Matsumoto H, Ueno D et al. Current status of multichannel electrogastrography and examples of its use. J ­Smooth Muscle Res 2013; 49: 78–88.

8. Bureš J, Kopáčová M, Voříšek V et al. Stanovení rychlosti evakuace žaludku pomocí dechového testu s 13C-oktanovou kyselinou. Metodika testu pro dospělé a výsledky vyšetření zdravých dobrovolníků. Čas Lék Čes 2005; 144(3): 18–22.

9. Bureš J, Kopáčová M, Voříšek V et al. Cor­relation of electrogastrography and gastric emptying rate estimated by ­13C-octanoic acid breath test in healthy volunteers. Folia Gastroenterol Hepatol 2007; 5(1): 5–11.

10. Dolina J, Dítě P, Přecechtělová M et al. 24hodinová pH-metrie a elektrogastrografie u nemocných s chronickou pankreatitidou. Čes a Slov Gastroent 1999; 53(6): 183–186.

11. Dolina J, Vlčková P, Hep A et al. Diabetická gastroparéza – využití elektrogastrografie. Diabetologie 2006; 9(2): 75–78.

12. Gürlich R, Maruna P, Frasko R. Transcutaneous electrogastrography in the perioperative period in patients undergoing laparoscopic cholecystectomy and laparoscopic non-adjustable gastric banding. Obes Surg 2003; 13(5): 714–720.

13. Bures J, Kabelac K, Kopacova M et al. Electrogastrography in patients with Roux-en-Y reconstruction after previous Billroth gastrectomy. Hepatogastroenterology 2008; 55(85): 1492–1496.

14. Frasko R, Maruna P, Gurlich R et al. Transcutaneous electrogastrography in patients with ileus. Relations to inter­leukin-1beta, interleukin-6, procalcitonin and ­C-reactive protein. Eur Surg Res 2008; 41(2): 197–202. doi: 10.1159/000134918.

15. Maruna P, Frasko R, Lindner J. Disturbances of gastric electrical control activity after laparotomic cholecystectomy are related to interleukin-6 concentrations. Eur Surg Res 2009; 43(4): 317–324. doi: 10.1159/000235569.

16. Varayil JE, Ali SM, Tacheci I et al. Electrogastrography in experimental pigs. Methodical design and initial experience. Folia Gastroenterol Hepatol 2009; 7(3–4): 98–104.

17. Květina J, Varayil JE, Ali SM et al. Pre­clinical electrogastrography in experimental pigs. Interdiscip Toxicol 2010; 3(2): ­53–58. doi: 10.2478/v10102-010-0011-5.

18. Ali SM, Varayil JE, Tachecí I et al. Electrogastrography in experimental pigs. The power analysis. Gastroent Hepatol 2011; 65(6): 325–330.

19. Tachecí I, Květina J, Kuneš M et al. The effect of general anaesthesia on gastric myoelectric activity in experimental pigs. BMC Gastroenterol 2013; 13: 48. doi: 10.1186/1471-230X-13-48.

20. Kararli TT. Comparison of the gastrointestinal anatomy, physiology, and biochemistry of humans and commonly used laboratory animals. Biopharm Drug Dispos 1995; 16(5): 351–380.

21. Swindle MM (ed.). Swine in the laboratory: surgery, anesthesia, imaging, and experimental techniques. 2. ed. London: CRC Press 2007.

22. Suenderhauf C, Parrott N. A physiologically based pharmacokinetic model of the minipig: data compilation and model implementation. Pharm Res 2013; 30(1): 1–15. doi: 10.1007/s11095-012-0911-5.

23. Explanatory report on the European convention for the protection of vertebrate animals used for experimental and other scientific purposes (ETS 123). Strasbourg: Council of Europe 2009.

24. Jones MP, Hoffman S, Shah D et al. The water load test: observations from healthy controls and patients with functional dyspepsia. Am J Physiol Gastrointest Liver Physiol 2003; 284(6): G896–G904.

25. Chen CL, Hu CT, Lin HH et al. Clinical utility of electrogastrography and the water load test in patients with upper gastrointestinal symptoms. J Smooth Muscle Res 2006; 42(5): 149–157.

26. Kopacova M, Tacheci I, Kvetina J et al. Wireless video capsule enteroscopy in preclinical studies: methodical design of its applicability in experimental pigs. Dig Dis Sci 2010; 55(3): 626–630. doi: 10.1007//s10620-009-0779-3.

27. Tacheci I, Kvetina J, Bures J et al. Wireless capsule endoscopy in enteropathy induced by nonsteroidal anti-inflammatory drugs in pigs. Dig Dis Sci 2010; 55(9): ­2471–2477. doi: 10.1007/s10620-009-1066-z.

28. Tacheci I, Kvetina J, Kunes M et al. Effect of different volume challenge on the gastric myoelectric activity in experimental pigs. UEG Journal 2013; 1 (Suppl 1): A400.

29. Tacheci I, Kvetina J, Kunes M et al. Electrogastrography in experimental pigs: the influence of gastrointestinal injury induced by dextran sodium sulphate on porcine gastric erythromycin-stimulated myoelectric activity. Neuro Endocrinol Lett 2011; 32 (Suppl 1): 131–136.

30. Zdarova Karasova J, Zemek F et al. Intravenous application of HI-6 salts (dichloride and dimethansulphonate) in pigs: comparison with pharmacokinetics profile after intramuscular administration. Neuro Endocrinol Lett 2013; 34 (Suppl 2): 74–78.

31. Bures J, Kvetina J, Pavlik M et al. Impact of paraoxon followed by acetylcholinesterase reactivator HI-6 on gastric myoelectric activity in experimental pigs. Neuro Endocrinol Lett 2013; 34 (Suppl 2): 79–83.

32. Bures J, Kvetina J, Pavlik M et al. Effect of different doses of atropine on the gastric myoelectric activity in experimental pigs. Gastroenterology 2014; 146 (5 Suppl): S267.

33. International programme on chemical safety evaluation. Antidotes for poisoning by organophosphorus pesticides. Monograph on Atropine. Geneva: World Health Organisation 2002. [online]. Available from: http://www.inchem.org/documents//antidote/antidote/atropine.htm#8.0.

34. Brown JH, Taylor P. Muscarinic receptor agonists and antagonists. In: Brunton L, Lazo JS, KL Parker KL (eds). Goodman & Gilman’s Pharmacological Basis of Therapeutics. 11. ed. New York: McGraw Hill 2006.

Labels
Paediatric gastroenterology Gastroenterology and hepatology Surgery

Article was published in

Gastroenterology and Hepatology

Issue 3

2014 Issue 3

Most read in this issue
Login
Forgotten password

Don‘t have an account?  Create new account

Forgotten password

Enter the email address that you registered with. We will send you instructions on how to set a new password.

Login

Don‘t have an account?  Create new account