Morphometric Parameters of Nucleiof EBV-Positive and EBV-Negative Hodgkin’sLymphoma Cells


Authors: J. Mačák ;  P. Řiháková
Authors‘ workplace: Ústav patologie LF UP, Olomouc Laboratoř molekulární patologie. Centrum molekulární biologie a medicíny LF UP, Olomouc
Published in: Čes.-slov. Patol., , 2001, No. 2, p. 57-60
Category:

Overview

Five morphometric parameters of nuclei of EBV-positive and EBV-negative Hodgkin’s lymphomacells were assessed for length, width, area, circumference, and circularity. For the measurementof the nuclei of the tumor cells (Hodgkin, Reed-Sternberg cells) the system of image analysis„Lucie“ was used. In comparison with EBV-positive Reed-Sternberg cells, the nuclei of the EBV -negative Reed-Sternberg cells had significantly larger circumference, area and width. The nucleiof the Hodgkin cells in EBV-negative Hodgkin’s lymphomas had significantly larger width andcircularity. The authors assume that the altered morphometric parameters are related to a latentEBV infection.

Key words:
Hodgkin’s lymphoma - EBV-positivity - morphometry of nuclei

Full text is not available online.
If interested in a scan of this journal, contact NTO ČLS JEP.

Labels
Anatomical pathology Forensic medical examiner Toxicology
Login
Forgotten password

Don‘t have an account?  Create new account

Forgotten password

Enter the email address that you registered with. We will send you instructions on how to set a new password.

Login

Don‘t have an account?  Create new account