#PAGE_PARAMS# #ADS_HEAD_SCRIPTS# #MICRODATA#

Assessment of theRatio of the D- and L- Form of Aspartic Acid in Tissue ofthe Achilles Tendon as an Indicator of Age


Authors: A. Pilin;  R. Čabala;  F. Pudil;  V. Bencko
Authors‘ workplace: Ústav soudního lékařství a toxikologie 1. LF UK a VFN Praha Katedra analytické chemie PF UK, Praha Fakulta potravinářské a biochemicé technologie VŠCHT, Praha Ústav hygieny a epidemiologie 1. LF UK, Praha
Published in: Čes.-slov. Patol., , 2001, No. 2, p. 27-29
Category:

Overview

The presence of the D- form of aspartic acid was detected in collagen of dentin and the interver-tebral disk before and assessment of its racemization coefficient was used for assessment of theage of subjects. Another tissue formed almost solely by collagen type I are tendons. Tendon tissuewas not investigated so far with regard to the racemization coefficient and therefore the authorsassessed the D-form of aspartic acid in the Achilles tendon. They used lyophilized tendon excisi-ons which were hydrolyzed. Amino acids in the hydrolysate were derived to N-TFA isopropylesters which were assessed by gas chromatography on a chiral capillary column. In all samplesthe D-form of aspartic acid was detected. The values of the racemization coefficient suggest thepossible use of thus processed tissue with certain limitations.

Key words:
assessment of age - Achilles tendon - aspartic acid - racemization

Full text is not available online.
If interested in a scan of this journal, contact NTO ČLS JEP.

Labels
Anatomical pathology Forensic medical examiner Toxicology
Login
Forgotten password

Enter the email address that you registered with. We will send you instructions on how to set a new password.

Login

Don‘t have an account?  Create new account

#ADS_BOTTOM_SCRIPTS#