Indirect Calorimetry in the Treatment of Metabolic Problems in Critically Ill Children
I. Novák; V. Dedek; M. Fajt; J. Hrdlička
Klinika pediatrie IPVZ, Fakultní Thomayerova nemocnice, Praha, přednosta doc. MUDr. I. Novák, CSc.
Čes-slov Pediat 1999; (11): 621-627.
To obtain objective information on the metabolic situation in critically sick children in intensivecare units as a baseline for treating adverse metabolic conditions.Method: Indirect calorimetry by means of a Deltatrac II Datex/Engström apparatus in spontaneously breathingand artificially ventilated children.Department: Intensive care unit, Paediatric Clinic IPVZ, Thomayer Hospital, Prague.Patients: In the course of three years 409 examinations were made of 150 children aged 2 days to 18 years, incl.21 with artificial pulmonary ventilation. Among these children a group of 71 children was selected regardless ofage, severity of the condition and diagnosis where indirect calorimetry revealed an increased protein utilization(more than 20% ratio of REE) as energy substrate. This group was analyzed further as regards objective metabolicindicators which can be assessed by indirect calorimetry.Results: The criterion of serious catabolism is reduction of REE by more than 25% of the appropriate valuesand protein utilization exceeding 30% of the assessed REE. There were 31/71 (71%) such p atients in the authors’group. In all metabolic intervention was attempted (branched amino acids as the main energy substrate in completeparenteral nutrition, temporary elimination of fats and restriction of non-protein sources of energy). In 22/31 theauthors succeeded and a favourable metabolic situation was achieved. In nine patients they failed. Seven of thelatter died (the mortality rate in the whole group suffering from catabolism was 8/71).Conclusion: Indirect calorimetry provides valid, non-invasive and immediate information on the metabolicsituation of critically ill children under conditions of intensive care. It is important that the authors were able todefine criteria of severe catabolism (REE lower than BMR by more than 25% and protein utilization exceeding
Full text is not available online.
If interested in a scan of this journal, contact NTO ČLS JEP
General practitioner for children and adolescents