Tubulo-squamous polyp of the vagina


Authors: M. Petrová 1;  J. Laco 2;  K. Červíček 3;  M. Tomšová 1
Authors‘ workplace: Oddělení patologické anatomie, Oblastní nemocnice Náchod, a. s., prim. MUDr. M. Tomšová, Ph. D., MBA 1;  Fingerlandův ústav patologie, LF UK a FN, Hradec Králové, prof. MUDr. A. Ryška, Ph. D. 2;  MUDr. Karel Červíček s. r. o, privátní gynekologická ambulance, pracoviště expertní kolposkopie Trutnov 3
Published in: Čes. Gynek.2015, 80, č. 3 s. 173-175

Overview

Objective:
To decribe a case of rare type of vaginal polyp.

Design:
Case report.

Setting:
Department of Pathological Anatomy, Regional hospital Nachod.

Conclusion:
Tubulo-squamous polyp is rare type of vaginal polyp first described in 2007, with only up to 20 cases have been reported in the literature so far. It affects mostly postmenopausal women and presents as a polypoid mass occurring in the upper part of vagina. Histologically, it is composed of squamous and glandular component within fibrous stroma. The etiopathogenesis of this lesion remains unclear, but it may arise from mesonephric remnants or Skene glands (so-called female prostate). This theory is supported by the fact that some cases show expression of prostate specific acid phosphatase (PSAP) and/or prostate specific antigen (PSA).

Keywords:
vagina, tubulo-squamous polyp, Skene glands


Sources

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2. Curman, RJ., Carcangiu, ML., Herrington, CS., Young, RH. WHO classification of tumours of female reproductive organs. 4th ed. Lyon: IARC, 2014, p. 213.

3. Dundr, P., Povýšil, C., Mára, M., Kužel, D. Tubulo-squamous polyp of the vagina. Cs Patol, 2008, 44, 2, p. 45–47.

4. McCluggage, WG., Young, RH. Tubulo-squamous polyp: a report of ten cases of a distinctive hitherto uncharacterized vaginal polyp. Am J Surg Pathol, 2007, 31, 7, p. 1013–1019.

5. Kazakov, DV., Stewart, CJR., Kacerovska, D., et al. Prostatic-type tissue in the lower female genital tract: a morphologic spectrum, including vaginal tubulosquamous polyp, adenomyomatous hyperplasia of paraurethral Skene glands (female prostate), and ectopic lesion in the vulva. Am J Surg Pathol, 2010, 34, 7, p. 950–955.

6. Stewart, CJR. Tubulo-squamous vaginal polyp with basaloid epithelial differentiation. Int J Gynecol Pathol, 2009, 28, 6, p. 563–566.

7. Tong, B., Clarke, BA., Ghazarian, D. Tubulo-squamous polyp with mucinous and goblet cell differentiation: a unique morphologic variant. Int J Gynecol Pathol, 2011, 30, 5, p. 518–519.

8. Vassallo, L., Lio, R., Vestri, M., Miracco, C. Tubulo-squamous polyp of the vagina. A case with cellular, "angiomyofibroblastic-like" stroma. Pathologica, 2012, 104, 1, p. 38–41.

Labels
Paediatric gynaecology Gynaecology and obstetrics Reproduction medicine

Article was published in

Czech Gynaecology

Issue 3

2015 Issue 3

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