Follow-up after the treatment of ovarian cancer – really without Ca 125?

Authors: P. Freitag
Authors‘ workplace: Gynekologicko-porodnická klinika 1. LF UK a VFN, Praha přednosta prof. MUDr. A. Martan, DrSc.
Published in: Čes. Gynek.2012, 77, č. 6 s. 540-542


Results of study MRC OV05 and EORTC/GCCG 55955 (Rustin et al.) have raised a considerable interest and controversy by questioning the early beginning of recurrent ovarian cancer treatment and the role of Ca 125 monitoring in the follow-up of ovarian cancer patients. Main pitfalls and limitations of this study are introduced in a survey. On their basis an author´s opinion on the continuing role of Ca 125 monitoring is expressed with a possible benefit for the subgroup of patients with a solitary or operable relaps or those with new treatment possibilities or with inclusion to new clinical studies.

Key words:
ovarian cancer, follow-up, Ca 125.


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Paediatric gynaecology Gynaecology and obstetrics Reproduction medicine

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