Quiscent trophoblastic disease

Czech version

Authors: F. Hron; V. Hejda; J. Feyereisl; P. Šafář; H. Sochová
Authors‘ workplace: Ústav pro péči o matku a dítě, Praha, ředitel doc. MUDr. J. Feyereisl, CSc. ; Centrum pro trofoblastickou nemoc v ČR, Praha
Published in: Ceska Gynekol 2011; 76(6): 443-446
Category: Original Article

Overview

Type of study:
Case report.

Setting:
Center for trophoblastic disease in Czech Republic, Institute for care of mother and child, 3^rdFaculty of Medicine of Charles University Prague.

Methods:
The autors present a case of quiscent trophoblastic disease diagnosed at 27 years old primipara, secundigravida after previous molar pregnancy. The patient had low levels of serum hCG present for more than 18 months after the termination of pregnancy. After this period there was a malignant transformation associated with rapid elevation of hCG levels with need for chemotherapy which was succesfully completed.

Conclusion:
Quiscent (dormant, noninvasive) trophoblastic disease is a recently described unit defined by low levels of hCG present in patients serum and urine samples without any evidence of trophoblastic tumour or other source of hCG production. Quiscent trophoblastic disease is associated with high risk of malignant transformation.

Key words:
quiscent, trophoblastic, noninvasive, persistent, hCG.

Sources

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