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Streptococci group B in perinatology


Authors: K. Biringer 1;  K. Biskupská Boďová 1;  M. Haško 1;  K. Dókuš 1;  J. Danko 1;  L. Štillová 2;  Z. Biringerová 3
Authors‘ workplace: Gynekologicko-pôrodnícka klinika JLF UK, Martin, Slovensko, prednosta prof. MUDr. J. Danko, CSc. 1;  Neonatologická klinika JLF UK, Martin, Slovensko, prednosta prof. MUDr. M. Zibolen, CSc. 2;  Klinika anesteziológie a intenzívnej medicíny JLF UK, Martin, Slovensko, prednosta doc. MUDr. B. Sániová, CSc. 3
Published in: Ceska Gynekol 2010; 75(5): 435-438

Overview

Objective:
Assessment of screening and prophylaxis of streptococci group B (GBS).

Design:
Retrospective study.

Setting:
Department of Gynecology and Obstetrics, Jessenius Faculty of Medicine, Comenius University, Martin, Slovak Republic.

Methods:
Groups of patients: A–GBS negative (n=601), B–GBS positive (n=166), and C–unknown GBS status (n=238).

Results:
We assessed 1005 deliveries; antenatal screening was done in 767 patients (166 GBS positive). Intrapartal antibiotic prophylaxis (IAP) was the most frequent in group B (75.3%), (A–10.0%, C–15.0%). The most common antibiotics: ampicillin, and cephalosporins of the 1st and 2nd generation. The interval from rupture of membranes (ROM) to the first IAP dose was significantly the shortest in group B. The longest interval from ROM to delivery was in group A (490 min.).

Conclusion:
This study shows the possibilities for improvement in GBS prophylaxis, in unknown GBS status, and preterm delivery, particularly.

Key words:
streptococci, GBS, perinatology, sepsis, morbidity, mortality.


Sources

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7. Moore, MR., Schrag, SJ., Schuchat, A. Effects of intrapartum antimicrobial prophylaxis for prevention of group B streptococcal disease on the incidence and ecology of earlyonset neonatal sepsis. Lancet Infect Dis, 2003, 3, p. 201–213.

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Labels
Paediatric gynaecology Gynaecology and obstetrics Reproduction medicine
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