Screening of cervical cancer – update


Authors: V. Dvořák 1;  J. Ondruš 2
Authors‘ workplace: Centrum ambulantní gynekologie a primární péče, Brno, vedoucí MUDr. V. Dvořák 1;  Centrum gynekologické onkologické prevence Havířov, vedoucí MUDr. J. Ondruš, M. I. A. C. 2
Published in: Čes. Gynek.2010, 75, č. 1 s. 65-68

Overview

Objective:
Update screening of cervical cancer.

Design:
Review article.

Setting:
Out-patient Gynaecology and Primary Care Centre, Brno.

Methods:
Study of the current literature.

Conclusion:
The persistent infection by human papillomavirus is a necessary condition for development of cervical cancer. Screening activity has an influence on it. Current screening is based on regular PAP smear. It should be evaluated by laboratory with accreditation and quality control. HPV test is too expansive for routine connection with screening for the most European countries.

Key word:
cervical cancer, screening, PAP smear, HPV test.


Sources

1. ALTS Group. Human papillomavirus testing for triage of women with cytologic evidence of low – grade squamous intraepithelial lesions: baseline data from a randomized trial. J National Cancer Institute, 2000, 92(5), p. 397–402.

2. Arbyn, M., Autier, R., Ferlay, J. Burden of cervical cancer in the 27 member states of the European Union, Estimates for 2004. Ann Oncol, 2007, 18, p. 1425–1427.

3. Ball, C., Madden, JE. Update on cervical cancer screening: Current diagnostic and evidence-based management protocols. Postgrad Med 2003, 113, 2.

4. Castle, PE. Basic science: beyond human papillomavirus: the cervix, exogenous secondary factors, and the development of cervical precancer and cancer. J Lower Genital Tract Dis, 2004, 8, 3, p. 224–230.

5. Coleman, DV. Internal quality control for cervical cytopathology laboratories. Cytopathology, 1996, 7, p. 1–3.

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17. Schenck, U., Planding, W. Quality assurace by continuous recording of the microscope status. Acta Cytol, 1996, 40, p. 73–80.

18. Solomon, D., Nayar, R. The Bethesda System of Reporting Cervical Cytology, definitions, criteria and explanatory notes, 2nd ed. New York: Springer, 2004, p. 191.

19. Solomon, D., Papillo, JL., Davey, DD. Statement on HPV DNA Test Utilization. Acta Cytol, 2009, 53, 3, p. 249–250

20. Syrjanen, S., Shabolova, IP., Petrovichev, N., et al. Human papillomavirus testing and conventional pap smear cytology as optional screening tools of women at different risk for cervical cancer in the countries of the former Soviet Union. J Lower Genital Tract Dis, 2002, 6, 2, p. 97–110.

21. Winer, RL., Kiviat, NB., et al. Development and duration of human papillomavirus lesions, after initial infection. J Infect Dis, 2005, 191, p. 731–738.

Labels
Paediatric gynaecology Gynaecology and obstetrics Reproduction medicine
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