Angiolipoleiomyóm maternice.
Kazuistika a prehľad literatúry


Authors: K. Kajo 1;  P. Žúbor 2;  Š. Krivuš 1;  J. Danko 2
Authors‘ workplace: Ústav patologickej anatómie Jesseniovej lekárskej fakulty Univerzity Komenského a Martinskej fakultnej nemocnice, Martin, vedúci prof. MUDr. L. Plank, CSc. 1;  Gynekologicko-pôrodnícka klinika Jesseniovej lekárskej fakulty Univerzity Komenského a Martinskej fakultnej nemocnice, Martin, vedúci prof. MUDr. J. Danko, CSc. 2
Published in: Čes. Gynek.2010, 75, č. 1 s. 54-56

Overview

Objective:
The rare case presentation of angiolipoleiomyoma (ALLM) of the uterus with review of diagnostic and discriminative information for this entity.

Subject:
Case report with review of the literature.

Setting:
Department of Pathology and Obstetrics and Gynecology at Jessenius Medical Faculty in Martin.

Conclusion:
The ALLM of the uterus is rare benign mixed mesenchyme tumor consisting of smooth muscle bundles, foci of mature fat tissue and abnormal vessels.

The presented case is describing a 53-year-old women hysterectomized for multiple uterine myoma of which two showed the histological signs of ALLM. On imunohistochemical profile are these tumors negative for melanocytic features, e.g. HMB-45, what distinguishes them from angiomyolipomas, which are currently categorized into so called PEComas – tumors originating from perivascular epithelial cells.

Key words:
uterus, leiomyoma, angiolipoleiomyoma, angiomyolipoma, PEComa.


Sources

1. Boisclair, J., Doré, M. Vet Pathol, 2001, 38, 6, p. 726-728.

2. Braun, HL., Wheelock, JB., Amaker, BH., Seeds, JW. Sonographic evaluation of a uterine angiolipoleiomyoma. J Clin Ultrasound, 2002, 30, 4, p. 241–244.

3. Cil, AP., Haberal, A., Hucumenoglu, S., et al. Angiomyolipoma of the uterus associated with tuberous sclerosis: case report and review of the literature. Gynecol Oncol, 2004, 94, 2, p. 593-596.

4. Clement, BC., Young, RH. Atlas of gynecologic surgical pathology. 2nd ed. Philadelphia: Saunders Elsevier, 2008, p. 516.

5. Demopoulos, RI., Denarvaez, F., Kaji, V. Benign mixed mesodermal tumors of the uterus: a histogenetic study. Am J Clin Pathol, 1973, 60, 3, p. 377–383.

6. Fadare, O. Uterine PEComa: appraisal of a controversial and increasingly reported mesenchymal neoplasm. Int Semin Surg Oncol, 2008, 6, 5, p. 7.

7. Honoré, LH. Uterine fibrolipoleiomyoma: report of a case with discussion of histogenesis. Am J Obstet Gynecol, 1978, 132, 6, p. 635-636.

8. Huang, PC., Chen, JT., Ho, WL. Clinicopathologic analysis of renal and extrarenal angiomyolipomas: report of 44 cases. Chin Med J (Taipei), 2000, 63, 1, p. 37–44.

9. Jacobs, DS., Cohen, H., Johnson, JS. Lipoleiomyomas of the uterus. Am J Clin Pathol, 1965, 44, p. 45–51.

10. Laffargue, F., Giacalone, PL., Charpin, C., Lachard, A. Uterine angiomyolipoma associated with pregnancy. Gynecol Oncol, 1993, 50, 3, p. 357–360.

11. Lo, RV., Santangelo, M., Fibbi, ML., et al. Benign lipomatous lesions of the uterus: 3 new cases, review of the literatures and histogenetic consideration. Appl Pathol, 1987, 5, 4, p. 220–228.

12. Makino, E., Yamada, J., Tada, J., et al. Cutaneous angiolipoleiomyoma. J Am Acad Dermat, 2008, 54, 1, p. 167-171.

13. McKeithen, SW., Shinner, J., Michelsen, J. Hamartoma of the uterus, report of a case. Obstet Gynecol, 1964, 24, p.231–234.

14. Ren, LR., Wu, HH. Pathologic quiz case. A 40-year-old woman with an unusual uterine tumor. Arch Pathol Lab Med, 2004, 128, 2, p. e31-e32.

15. Shintaku, M. Lipoleiomyomatous tumors of the uterus: a heterogeneous group? Histopathological study of five cases. Pathol Int, 1996, 46, 7, p. 498–502.

16. Sieinski, W. Lipomatous neometaplasia of the uterus: report of 11 cases with discussion of histogenesis and pathogenesis. Int J Gynecol Pathol, 1989, 8, 4, p.357–363.

17. Volpe, R., Canzonieri, V., Gloghini, A., Carbone, A. Lipoleiomyoma with metaplastic cartilage (benign mesenchymoma) of the uterine cervix. Pathol Res Pract, 1992, 188, 6, p. 799– 801.

18. Yaegashi, H., Moriya, T., Soeda, S., et al. Uterine angiomyolipoma: case report and review of the literature. Pathol Int, 2001, 51, 11, p. 896–901.

Labels
Paediatric gynaecology Gynaecology and obstetrics Reproduction medicine
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