Surgical Treatment of Supratentorial Cortico‑ subcortical Cavernous Malformation

Authors: M. Májovský;  D. Netuka;  O. Bradáč;  V. Beneš
Authors‘ workplace: Neurochirurgická klinika 1. LF UK a ÚVN – VFN Praha
Published in: Cesk Slov Neurol N 2014; 77/110(5): 631-637
Category: Short Communication

Podpořeno IGA MZ NT 13627.


The aim of the study is to present surgical outcome of treatment of supratentorial cavernous malformation of the brain at the Department of Neurosurgery, Charles University and the Central Military Hospital in Prague.

Material and methods:
We retrospectively enrolled patients dia­gnosed between 2000 and 2012 with supratentorial, cortico‑ subcortically located cavernoma. We analysed epidemiological and radiological data, clinical presentation and surgical results including complications.

Initial symptoms included epileptic seizure (49%), headache (22%) and focal neurological deficit (19%); 15% of cavernomas were found incidentally. Radiological signs of recent haemorrhage on MR scans were found in 27% patients. We performed surgery in 145 patients with 158 cavernous malformations. Twenty five lesions were treated conservatively. Surgical complications occurred in 8% of patients. One patient died and one had permanent neurological deficit attributable to surgery. Postoperative seizure rate was significantly higher in a group with wound infection or postoperative hematoma (p < 0.05).

Microsurgical resection of lobar cavernoma is relatively safe procedure with minimal morbidity and mortality. Postoperative hematoma or wound infection might have an epileptogenic potential.

Key words:
cavernous malformation – microsurgery – epilepsy

The authors declare they have no potential conflicts of interest concerning drugs, products, or services used in the study.

The Editorial Board declares that the manu­script met the ICMJE “uniform requirements” for biomedical papers.


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