Neuroborreliosis Imitating Brain Tumour in Children and Vice Versa


Authors: L. Krbková 1;  L. Klapačová 1;  P. Mikolášek 1;  M. Charvátová 2;  I. Červinková 2;  J. Bednářová 3
Authors‘ workplace: Klinika dětských infekčních nemocí LF MU a FN Brno 1;  Klinika dětské radiologie LF MU a FN Brno 2;  Oddělení klinické mikrobiologie, FN Brno 3
Published in: Cesk Slov Neurol N 2014; 77/110(5): 620-623
Category: Short Communication

Overview

Tick‑ borne neuroinfections are rare among children with oncologic dia­gnosis. Nevertheless, the dia­gnostic procedure may be more complicated due to suspicion of the relapse of the primary illness. Despite typical symptoms of neuroborreliosis, including tick bite and early localized borreliosis –  erythema migrans, tumours of central nervous system have to be taken into account for the differential dia­gnosis in childhood.

Key words:
neuroborreliosis – intrathecally produced antibodies – brain tumors – magnetic resonance imaging

The authors declare they have no potential conflicts of interest concerning drugs, products, or services used in the study.

The Editorial Board declares that the manu­script met the ICMJE “uniform requirements” for biomedical papers.


Sources

1. Christen HJ. Lyme neuroborreliosis in children. Ann Med 1996; 28(3): 235– 240.

2. Tuerlinckx D, Glupczynski Y. Lyme neuroborreliosis in children. Expert Rev Anti Infect Ther 2010; 8(4): 455– 463. doi: 10.1586/ eri.10.15.

3. Pachner AR, Steiner I. Lyme neuroborreliosis: infection, immunity, and inflammation. Lancet Neurol 2007; 6(6): 544– 552.

4. Wilne S, Collier J, Kennedy C, Koller K, Grundy R, Walker D. Presentation of childhood CNS tumours: a systematic review and meta‑analysis. Lancet Oncol 2007; 8(8): 685– 695.

5. Halperin JJ. Nervous system Lyme disease. Infect Dis Clin N Am 2008; 22(2): 261– 274. doi: 10.1016/ j.idc.2007.12.009.

6. Stanek G, Fingerle V, Hunfeld KP, Jaulhac B, Kaiser R,Krause A et al. Lyme borreliosis: clinical case definition for dia­gnosis and management in Europe. Clin Microbio­l Infect 2011; 17(1): 69– 79. doi: 10.1111/ j.1469‑ 0691.2010.03175.x.

7. Mygland A, Ljostad U, Fingerle V, Rupprecht T, Schmutzhard E, Steiner I. EFNS guidelines on the dia­gnosis and management of European Lyme neurobor­reliosis. Eur J Neurol 2010; 17(1): 8– 16. doi: 10.1111/ j.1468‑ 1331.2009.02862.x.

8. Murray R, Morawetz R, Kepes J, Gammal T, LeDoux M. Lyme neuroborreliosis manifesting as an intracranial mass lesion. Neurosurgery 1992; 30(5): 769– 773.

9. Curless RG, Schatz NJ, Bowen BC, Rodriguez Z,Ruiz A. Lyme neuroborreliosis masquerading as a brainstem tumor in a 15‑year‑ old. Pediatr Neurol 1996; 15(3): 258– 260.

10. Latsch K, Tappe D, Warmuth‑ Metz M, Hebestreit H. Central nervous system borreliosis mimicking pontine tumor. J Med Microbio­l 2006; 55(11): 1597– 1599.

Labels
Paediatric neurology Neurosurgery Neurology

Article was published in

Czech and Slovak Neurology and Neurosurgery

Issue 5

2014 Issue 5

Most read in this issue
Login
Forgotten password

Don‘t have an account?  Create new account

Forgotten password

Enter the email address that you registered with. We will send you instructions on how to set a new password.

Login

Don‘t have an account?  Create new account