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Benefit of a single intra-articular injection of hyaluronic acid in the treatment of osteoarthritis

6. 11. 2020 Source: Osteoarthritis

Viscosupplementation serves as a minimally invasive procedure to restore the rheological properties of synovial fluid and alleviate pain in patients with symptomatic osteoarthritis (OA). We now have a new 3rd generation hyaluronic acid (HA) product for intra-articular injections –⁠ Hyruan One, which uses HA cross-linking technology. The following text summarizes its benefits in the pharmacological management of OA.

Injekce a biologická léčba

Efficacy and Safety of Single-Application Hyaluronic Acid in Osteoarthritis Therapy

Causal therapy for osteoarthritis does not yet exist. Patients suffering from progressive joint disease are thus dependent on symptomatic medications that alleviate symptoms and partially slow the…
6. 11. 2020 Source: Osteoarthritis
sestra podává injekci

Enoxaparin in Weight-Based Dosing for Thromboprophylaxis in Hospitalized Cancer Patients

Cancer patients are at higher risk of developing thromboembolic disease during hospitalization. Currently, there is not enough evidence supporting the efficacy and safety of the standard fixed dose…
6. 11. 2020 Source: Thromboprophylaxis

Neoadjuvant Immunotherapy in Resectable Non-Small Cell Lung Cancer

Antibodies against the programmed cell death protein 1 (PD-1) improve the survival of patients with advanced non-small cell lung cancer (NSCLC). However, their use has not yet been tested in patients…
6. 11. 2020 Source: Immunotherapy in Oncology
deprese žena vyhoření stres

Impact of Alpha-1 Antitrypsin Deficiency on Quality of Life and Mental Health of Patients

The clinical manifestation of alpha-1 antitrypsin deficiency and its impact on quality of life are highly heterogeneous. This contribution by pulmonologist Robert Sandhaus summarizes interesting…
3. 11. 2020 Source: Deficiency of Alpha-1-Antitrypsin
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COVID-19 and Immune Thrombocytopenic Purpura −⁠ Spanish Experience Suggests Surprising Connections

In a retrospective study examining the impact of COVID-19 on immune thrombocytopenic purpura, Spanish authors surprisingly observed a paradoxical effect.
2. 11. 2020 Source: Immune Thrombocytopenia
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Care of Dental Dentures According to the Recommendations of the American Society of Dental Prosthetists

Dental dentures are the most common solution for missing teeth in the jaw. They should serve patients for several years, so proper care is essential. Therefore, dental professionals should not only…
2. 11. 2020 Source: Optimal Care of Dentures
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Current Insights into the Antispasmodic and Analgesic Effects of Metamizole on the Gastrointestinal Tract

Brazilian authors published a review of available information on the mechanism of action of metamizole, its impact on gastrointestinal tract motility, its effect on the gastric mucosa, and its…
2. 11. 2020 Source: Analgesia
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Impact of Thyroid Dysfunction on the Cardiovascular System in Elderly Patients

The incidence of thyroid disease increases with age. In the Czech Republic, up to 5% of the population suffers from hypothyroidism, and the prevalence of hyperthyroidism is estimated at 0.2-1%. The…
2. 11. 2020 Source: Thyroid Disorders
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Rurioctocog alfa pegol in previously treated patients with severe hemophilia A: What findings did the long-term continuation study bring?

Rurioctocog alfa pegol (Adynovi) is a recombinant coagulation factor VIII modified by pegylation, which results in an approximately 1.5× prolonged biological half-life compared to standard half-life…
2. 11. 2020 Source: Hemophilia
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Position of aPCC in the Treatment of Hemophilia A Complicated by the Development of Inhibitors

Activated prothrombin complex concentrates (aPCC) are essential drugs that not only allow the control of bleeding in patients with congenital hemophilia A and inhibitors but also help to prevent such…
2. 11. 2020 Source: Hemophilia
štítná žláza grafika

Anxiety Disorders and Autoimmune Thyroiditis –⁠ A Connection Rather Than Coincidence?

Anxiolytics commonly target the central nervous system. Newly published research by Ukrainian authors offers a different perspective –⁠ according to their findings, anxiety may be related to thyroid…
29. 10. 2020 Source: Depression and Anxiety
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Targeted Treatment and Quality of Life in Patients with Follicular Lymphoma

The GALLIUM clinical trial evaluated chemotherapy in combination with targeted treatment using rituximab or obinutuzumab in previously untreated patients with advanced follicular lymphoma (FL). A…
27. 10. 2020 Source: Non-Hodgkin Lymphomas and CLL
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Sport Therapy as Part of Hemophilia Management

A study by authors from the University of Wuppertal in Germany specifically examined the impact of a half-year programmed sport therapy on the subjective physical performance and quality of life of…
27. 10. 2020 Source: Hemophilia with Movement
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EHL preparations have the potential to change the quality of life for people with hemophilia

Within the therapeutic modalities for hemophilia, the current era offers a number of preparations. Newer extended half-life (EHL) replacement therapies can provide hemophiliacs with better protection…
27. 10. 2020 Source: Hemophilia with Movement
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