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Different doses of LMWH in hospitalized patients with COVID-19 –⁠ interim experience

18. 11. 2020 Source: Thromboprophylaxis

Many experts recommend administering heparin to patients with COVID-19 as part of anticoagulant prophylaxis, especially in severe forms of this infection. However, data on dosage, administration duration, and the effectiveness of this approach are limited. Therefore, authors from Bologna, Italy, investigated the relationship between various doses of low-molecular-weight heparin (LMWH) and mortality in patients hospitalized with COVID-19.

Depakine Chrono versus Other Valproates in the Treatment of Bipolar Disorder

Bipolar disorder is among the most severe psychiatric illnesses, and if not treated properly, it can negatively affect the patient's quality of life. Does switching therapy from other valproates to…
18. 11. 2020 Source: Bipolar Disorder
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Efficacy of Romiplostim in Children with Persistent or Chronic ITP

The effect of the thrombopoietin receptor agonist romiplostim in adult patients with immune thrombocytopenia (ITP) is well known. Equally important, however, are data on its treatment in children —…
18. 11. 2020 Source: Immune Thrombocytopenia
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Experiences with AHA in Two Czech Centers and Risk Factor Evaluation

This summer, the journal Haemophilia published the results of an analysis of data from a relatively large Czech cohort of patients with acquired hemophilia A (AHA). The goal was to identify risk…
18. 11. 2020 Source: Hemophilia

Therapy of Chronic Leg Ulcers According to Evidence-Based Medicine

Chronic ulcers on the lower extremities are defined as trophic defects that show no signs of healing after 3 months of appropriate treatment or are not healed even after 12 months of treatment. Their...
15. 11. 2020 Source: Wound Healing
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FLEX –⁠ A New Predictive Model for Assessing Follicular Lymphoma Risks

Overall survival of patients with advanced-stage follicular lymphoma (FL) who experience early disease progression after chemotherapy remains low. Currently used clinical prognostic models do not…
14. 11. 2020 Source: Non-Hodgkin Lymphomas and CLL
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Socio-economic Benefits of Using Obinutuzumab in 1st Line Treatment of Follicular Lymphoma

Pharmacoeconomic analyses remind us that our patients' diseases affect not only themselves or the healthcare system, but also have an impact on the entire society. Patients with follicular lymphoma…
14. 11. 2020 Source: Non-Hodgkin Lymphomas and CLL

Expression of PD-L1 in Patients with Advanced Non-Small Cell Lung Cancer

An international team of authors published a systematic review addressing the relationship between the programmed cell death receptor ligand (PD-L1) and important clinical characteristics of patients…
14. 11. 2020 Source: Immunotherapy in Oncology
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Case Study with Voting: Intensification of Type 2 Diabetes Therapy in a Chronically Treated Patient. How to Proceed According to Current Recommendations?

We have prepared an interactive case study for you with a 70-year-old patient with decompensated Type 2 Diabetes. The patient was diagnosed with DM eight years ago. What treatment approach would you choose?...
12. 11. 2020 Source: Diabetes
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Levodropropizine vs. dextromethorphan: Which one to recommend to your patients and why?

Reducing cough intensity and nighttime awakenings, rapid onset of action, simple dosing regimen, and good treatment tolerance—these are the properties we expect from antitussive drugs, not only in…
12. 11. 2020 Source: Cough Therapy
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COVID Pneumonia: How Can Erdosteine Help and What Did a Clinical Study Suggest?

When patients who have recovered from COVID pneumonia begin home treatment, they are often far from being symptom-free. General practitioners and outpatient pulmonologists often have to address these…
12. 11. 2020 Source: Cough Therapy
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Improving Physical Function in Patients with COPD in Routine Clinical Practice

The increase in exercise capacity with the use of a fixed-dose combination of tiotropium and olodaterol in the Respimat inhaler has already been demonstrated in clinical studies in patients with chronic...
9. 11. 2020 Source: COPD
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Prostate Health Index and its Possible Use in Clinical Practice

With the increasing incidence of prostate cancer, the effort to improve its diagnostics is also growing. The exclusively used and practice-proven prostate-specific antigen (PSA) continues to play an…
9. 11. 2020 Source: Prostate Health Index
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Levothyroxine and the Interchangeability of Preparations Containing It

Levothyroxine is a synthetic thyroid hormone used to treat patients with hypothyroidism, which affects approximately 1-2% of the younger population and increases with age, especially in women.…
6. 11. 2020 Source: Thyroid Disorders
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Desirable Side Effects of Antidiabetics

The days when diabetology was a field solely focused on normalizing blood sugar levels are long gone. Today, the approach in diabetology increasingly prioritizes influencing the patient's overall…
6. 11. 2020 Source: Diabetes
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