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Why Are Mucolytics Beneficial for Patients with COPD?
15. 4. 2021 Source: Cough TherapyPart of the clinical picture of chronic obstructive pulmonary disease (COPD) includes mucus hypersecretion in the airways and its impaired clearance, resulting in a chronic productive cough. Mucus production requires management, just like dyspnea and cough. But what can be expected from mucolytic treatment?
Dual therapy improves not only lung function but also quality of life in COPD patients
Chronic obstructive pulmonary disease (COPD) reduces the quality of life of patients and is one of the main causes of morbidity and mortality. According to international recommendations, the initial…15. 4. 2021 Source: COPD
Therapy with Cyclosporine in the Context of the Coronavirus Pandemic
The rapid spread of the SARS-CoV-2 virus and the associated COVID-19 disease pandemic raises concerns about possible risks associated with immunosuppressive treatment of autoimmune diseases.…
Does dabigatran use in women with acute venous thromboembolism reduce the risk of uterine bleeding compared to warfarin?
The use of new oral anticoagulants (NOACs) in patients with deep vein thrombosis is associated with a more favorable safety profile compared to warfarin. However, direct factor Xa inhibitors…14. 4. 2021 Source: Anticoagulant Treatment
Effect of Short-Term and Long-Term Stress on Heart Rate Variability
Acute and chronic stress significantly affects the cardiovascular (CV) system. The study presented below examines the effects of both acute and chronic stress on heart rate variability in 50 healthy…13. 4. 2021 Source: Cardiovascular Continuum
Experiences with Long-term Treatment of Psoriasis with Interleukin 17A Inhibitor
The current publication of the long-term extension of the UNCOVER-3 study, which focused on the treatment of psoriasis with ixekizumab, describes the efficacy and safety of 4 years of use of this…13. 4. 2021 Source: Biological Treatment
Options for Preventing Enteral Nutrition Intolerance in Mechanically Ventilated Patients in the ICU
Standards of care for critically ill patients recommend enteral nutrition for those on mechanical ventilation. A recently published study addressed the question of how to identify patients at risk of…12. 4. 2021 Source: Enteral Nutrition
European Registry of Patients with Alpha-1 Antitrypsin Deficiency EARCO Enrolls Patients
Insufficient identification of patients with alpha-1 antitrypsin deficiency (AATD) and a lack of knowledge about this disease have led to the launch of the European Registry EARCO, which is currently…12. 4. 2021 Source: Deficiency of Alpha-1-Antitrypsin
Can alpha-1-antitrypsin deficiency affect severity and higher mortality in COVID-19 patients?
Alpha-1-antitrypsin (AAT) deficiency is commonly found in the European population. The most cases are recorded in countries with the highest COVID-19 mortality rates. Are there direct correlations?12. 4. 2021 Source: Deficiency of Alpha-1-Antitrypsin
Effectiveness of the Venetoclax/Rituximab Combination in the Treatment of CLL – 5-Year Follow-Up Data
At the virtual 62nd Annual Meeting of the American Society of Hematology (ASH), updated results of a clinical evaluation of the treatment of patients with refractory/relapsed chronic lymphocytic…12. 4. 2021 Source: Chronic Lymphocytic Leukemia
Retention – An Overlooked Parameter of Incontinence Products
In the Czech Republic and other European countries, the main criterion when choosing an incontinence product, apart from its size, is primarily absorption. This defines the amount of fluid the…9. 4. 2021 Source: Incontinence
Hemorrhoidal Disease – A Civilization Illness Responsible for Perianal Discomfort
According to estimates, almost every second Czech will experience at least one attack of hemorrhoidal disease. Symptomatic hemorrhoids are found in about 5% of the population. Prevalence depends to…8. 4. 2021 Source: Venous Insufficiency
Chemotherapy as a Risk Factor for Severe COVID-19 Course?
During the coronavirus pandemic, patients with malignant neoplastic diseases are considered an at-risk group. Whether chemotherapy is a risk factor for a more severe course of COVID-19 was the…8. 4. 2021 Source: Antiemetic Therapy
Impact of Antiemetic Prophylaxis on Quality of Life of Patients Treated with Chemotherapy – Data from Practice
Chemotherapy-induced nausea and vomiting (CINV) is a relatively common complication of cancer treatment with a significantly negative impact on patients' quality of life. A large prospective analysis…8. 4. 2021 Source: Antiemetic Therapy
Adjuvant Treatment of Early Invasive HER2+ Breast Cancer − Results of the Katherine Study
Women with breast cancer found to have residual invasive disease during surgery after neoadjuvant chemotherapy and HER2-targeted therapy have a significantly worse prognosis. For these patients, the…8. 4. 2021 Source: Breast Carcinoma
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