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Effect of Prostaglandin Analogues With and Without Preservatives on Meibomian Glands in Glaucoma Patients

31. 3. 2021 Source: Treatment of Glaucoma

Prostaglandin analogues (PGA) have become a standard in the treatment of open-angle glaucoma. However, their long-term use may be associated with eye irritation or damage to the Meibomian glands. The study presented below aimed to determine whether these changes are directly caused by PGAs or the preservatives in the eye drops.

Post-COVID Depression: How Can a General Practitioner Help?

Psychiatrists confirm that mental health plays an increasingly important role in the context of the COVID-19 pandemic. Although exact data will only be available over time, as the impacts in this…

30. 3. 2021 Source: Depression and Anxiety

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If Suicides Were COVID-19... or Why We Still Overlook a Significant Cause of Premature Deaths?

More than a year since the start of the pandemic, the SARS-CoV-2 coronavirus has claimed 2.8 million lives globally, with 127 million recorded cases of COVID-19 (as of March 29, 2021). According to…

30. 3. 2021 Source: Depression and Anxiety

Léky proti rakovinné buňce jako zdravotní péče lékařský koncept pro farmaceutický lék

Lorlatinib showed significant benefit in 1st line treatment of advanced ALK-positive non-small cell lung carcinoma

In the international CROWN study, lorlatinib compared to crizotinib led to a 72% reduction in the risk of disease progression or death and significant improvement in intracranial response to…

30. 3. 2021 Source: Genetic Profile and Treatment of NSCLC

Position of Parenteral Therapy in Patients with Severe COVID-19 Disease

Patients with severe COVID-19 disease are at risk of developing acute respiratory insufficiency requiring non-invasive or invasive pulmonary ventilation. Intensive care therapy is associated with a…

30. 3. 2021 Source: Parenteral Nutrition

Prevalence of Depression, Anxiety, and Stress in the Global Population During the COVID-19 Pandemic

A cross-sectional study assessed the prevalence and rate of depression, anxiety, and stress among individuals from various countries around the world during the ongoing COVID-19 pandemic and initial…

30. 3. 2021 Source: Depression and Anxiety

Does idarucizumab reverse the anticoagulant effect of dabigatran regardless of renal function?

The drugs idarucizumab and dabigatran are excreted by the kidneys. The RE-VERSE AD study investigated whether the renal function of patients affects the extent of the reversing effect of idarucizumab…

29. 3. 2021 Source: Anticoagulant Treatment

Profile of the effect of aclidinium bromide compared to glycopyrronium bromide

A study by Spanish authors examined the profiles of 2 long-acting muscarinic receptor antagonists (LAMA), aclidinium bromide and glycopyrronium bromide, under in vitro and in vivo conditions.

29. 3. 2021 Source: Treatment of Asthma and COPD

Genuair®/Pressair® Inhaler in the Treatment of COPD –⁠ Minimum Errors During Inhalation and High Patient Satisfaction

The article by German authors summarizes the results achieved with the Genuair® inhaler (marketed in the USA under the name Pressair®), highlighting its ease of use, simple patient training, low…

29. 3. 2021 Source: Treatment of Asthma and COPD

The Importance of Vitamin D for the Proper Function of the Immune System

The relationship between vitamin D and the immune system has been known for nearly 30 years, but only in recent years have we gained new insights that explain and further refine the physiological…

29. 3. 2021 Source: GI, colic and microbiome

Summary of Recommendations for the Treatment of Immune Thrombocytopenia in Pregnancy

Immune thrombocytopenia (ITP) is an autoimmune disorder characterized by a temporary or permanent reduction in the number of platelets, leading to an increased risk of bleeding. It also occurs in 1-5…

28. 3. 2021 Source: Immune Thrombocytopenia

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Teriflunomide and Pregnancy Planning

The authors of the article published last year in Multiple Sclerosis Journal present data regarding experiences with the use of teriflunomide during pregnancy.

25. 3. 2021 Source: Multiple Sclerosis

Interactive Case Study of a Patient with Severe Hemophilia A -⁠ Experience from Slovenia

Assoc. Prof. Dr. Irena Preložnik Zupan (University Medical Centre Ljubljana) describes an interactive case study of a patient with severe hemophilia A and progressive cataracts in both eyes.

24. 3. 2021 Source: Quality Life Even with Hemophilia

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New Treatment Options for Hemophilia Come with Discussions on Important Issues

The organizing committee of this year's virtual congress of the European Association for Haemophilia and Allied Disorders (EAHAD 2021) promised in the opening speech a "showcase of the latest…

24. 3. 2021 Source: Quality Life Even with Hemophilia

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Summary Analysis of HAVEN 1–4 and Patient Case Studies from ÚHKT

MUDr. Věra Geierová from the Institute of Hematology and Blood Transfusion in Prague prepared a summary of what was discussed about emicizumab during the ASH 2020 congress for this year's Prague…

24. 3. 2021 Source: Quality Life Even with Hemophilia

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