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Diagnosis of von Willebrand Disease Step by Step

27. 4. 2021 Source: Von Willebrand Disease

Von Willebrand disease (vWD) is the most common congenital bleeding disorder, with an estimated prevalence of 1/1000. It is classified into 3 types based on the form and extent of quantitative or qualitative deficiency. Diagnosis of vWD is a complex process that usually takes some time.

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Diabetic Nephropathy and COVID-19: Fatal Connection?

People with diabetes and diabetic kidney disease exhibit higher mortality and risk of severe illness in connection with COVID-19. The worse prognosis of these patients likely has multiple reasons; in…
26. 4. 2021 Source: Diabetes
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Role and Possibilities of Telemedicine in the Management of Hemophilia Care

A team of Irish experts recently evaluated the current possibilities of telemedicine in the care of individuals with hemophilia –⁠ not only from the perspective of care provided by specialized…
22. 4. 2021 Source: Hemophilia with Movement
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Manual Fascial Therapy in Patients with Hemophilic Arthropathy

Fascial therapy is a rehabilitative technique that mobilizes the fascial complex using manual techniques with the goal of improving tissue mobility and function, as well as influencing pain. A team…
22. 4. 2021 Source: Hemophilia with Movement
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Metamizole vs. Tramadol in Postoperative Analgesia

Metamizole and tramadol are well-known analgesics that have been used in practice for a long time. Interesting insights into these substances were provided by the studies presented below. Spanish…
19. 4. 2021 Source: Analgesia
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Spasmolytic Effect of Metamizole

A study aimed at clarifying the mechanism of action of metamizole suggested that the clinically proven effect of this analgesic on colicky pain originating from the biliary tract could be due to…
19. 4. 2021 Source: Analgesia
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PID in children manifest differently, 10 warning signs help in diagnosis

We asked MUDr. Eva Hlaváčková from the Department of Clinical Immunology and Allergology, Faculty of Medicine, Masaryk University, and St. Anne's University Hospital in Brno about the essential…
19. 4. 2021 Source: Primary and Secondary Immunodeficiencies
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Can sartans improve clinical outcomes in hypertensive patients with COVID-19?

Dysfunction of the renin-angiotensin system (RAS) has been detected in patients with COVID-19. This finding led to the hypothesis that RAS inhibitors (RASi) could help these patients. To verify this,…
19. 4. 2021 Source: Sartans in the Treatment of Hypertension

Candesartan is beneficial in heart failure with mildly reduced ejection fraction

Analysis of data from the CHARM study showed that in patients with heart failure with mildly reduced ejection fraction (HFmrEF 0.40–0.49), candesartan compared to placebo reduces the risk of death…
19. 4. 2021 Source: Sartans in the Treatment of Hypertension
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COVID-19 and MS: Do You Know the Risk Factors? What the American Registry Analysis Showed

An article published in the March issue of the prestigious journal JAMA Neurology summarizes the findings of an analysis of the course of COVID-19 in patients with multiple sclerosis in North…
19. 4. 2021 Source: Multiple Sclerosis

Fatigue in Multiple Sclerosis: What Can Teriflunomide Do?

An article by French authors published in January this year in the journal Multiple Sclerosis and Related Disorders evaluated the effect of teriflunomide on fatigue in patients with multiple…
19. 4. 2021 Source: Multiple Sclerosis
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Long-term effect of the triple combination of perindopril, indapamide, and amlodipine on left ventricular hypertrophy in hypertension

A recent open-label interventional study aimed to describe the long-term effect of a fixed triple combination of perindopril, indapamide, and amlodipine compared to a free combination of a RAAS…
18. 4. 2021 Source: ACE inhibitory
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Myths Accompanying Therapy of Arterial Hypertension

Arterial hypertension is among the most common yet most underestimated diseases in the adult population. Misinterpretation of data and inadequate management of this disease can be caused, among other…
18. 4. 2021 Source: ACE inhibitory
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Effect of Discontinuing Inhaled Corticosteroids in Patients with COPD in Real Clinical Practice

Inhaled corticosteroids are prescribed to patients with COPD to prevent disease exacerbation. However, in clinical practice, they are often overprescribed in non-indicated cases. A study conducted in…
16. 4. 2021 Source: COPD
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Impact of the COVID-19 Pandemic on People with Schizophrenia Spectrum Disorders

The COVID-19 pandemic has a far-reaching impact on the physical and mental health of the global population. The current situation poses an undue burden on patients suffering from schizophrenia as…
16. 4. 2021 Source: Schizophrenia and Antipsychotics
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