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Detection of von Willebrand Disease

23. 3. 2021 Source: Von Willebrand Disease

Von Willebrand disease (vWD) is an autosomal hereditary bleeding disorder. Its detection and diagnosis require several steps, including the initial suspicion of the presence of this disease.

dedek demence lecba stařeček

Can the Use of Statins Help Reduce the Risk of Dementia?

A meta-analysis published last year by Taiwanese experts evaluated the connection between the use of statins and the incidence of dementia. What conclusions did the authors reach?
23. 3. 2021 Source: Cardiovascular Risks
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Statin Therapy May Reduce Mortality in Patients Hospitalized with COVID-19

In connection with the COVID-19 pandemic, intensive research is ongoing to understand the impact of patients' chronic medication on the prognosis of the disease. A recently published Spanish study…
23. 3. 2021 Source: Cardiovascular Risks
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Reasons for Nonadherence to Statin Therapy -⁠ Survey Results Among Patients

Adherence to statin therapy remains suboptimal despite its proven benefits in reducing cardiovascular risk in individuals with dyslipidemia. Recently published survey results conducted among patients…
23. 3. 2021 Source: Cardiovascular Risks
Ilustrační záběr na muže v nemocniční posteli s měřením srdeční činnosti na prstu.

Regorafenib and Trifluridine/Tipiracil: Hospitalization and Clinical Outcomes in the Treatment of Metastatic Colorectal Cancer

Regorafenib and trifluridine/tipiracil are drugs that prolong overall survival (OS) in pre-treated patients with metastatic colorectal cancer (mCRC). The difference in the toxicity of these agents…
22. 3. 2021 Source: Treatment of Gastrointestinal Carcinomas
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Does the type of oral anticoagulant affect heparin dosing during catheter ablation?

During catheter ablation, which patients undergo as part of atrial fibrillation (AF) treatment, current guidelines recommend the administration of heparin without interrupting oral anticoagulant…
22. 3. 2021 Source: Anticoagulant Treatment
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Post-COVID-19 Patient Care from the Perspective of Experts Across Fields

For many patients with COVID-19, overcoming the acute phase is crucial, but we now know that the disease may not end there. Some patients even manage the acute stage with very mild symptoms, and…
19. 3. 2021 Source: Cough Therapy
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Familial Hypercholesterolemia and COVID-19: Connections and Risks

Patients with familial hypercholesterolemia (FH) likely have a higher risk of COVID-19 complications both in the acute phase of the infection and for a relatively long period after its occurrence.
18. 3. 2021 Source: Hypercholesterolemia
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Is Baricitinib Suitable for Long-Term Treatment of Rheumatoid Arthritis?

The nature of rheumatoid arthritis requires effective and long-term treatment. The current analysis of data from the long-term extension RA-BEYOND reveals the potential of baricitinib in maintaining…
12. 3. 2021 Source: Biological Treatment
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INTERACTIVE CASE STUDY of a patient with mCRC treated long-term with various modalities

MUDr. Stanislav John, Ph.D., Clinic of Oncology and Radiotherapy, Faculty of Medicine, Charles University and University Hospital Hradec Králové
11. 3. 2021 Source: Colorectal Cancer
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Thromboprophylaxis with Enoxaparin Reduces Mortality in Patients Hospitalized with COVID-19

Severe acute respiratory syndrome caused by COVID-19 is associated with a hypercoagulable state and an increased risk of thrombotic events. Since the beginning of the pandemic, thromboprophylaxis has…
11. 3. 2021 Source: Thromboprophylaxis
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Virtual Echocardiography as a Potential Screening Tool for the Diagnosis of Primary Pulmonary Hypertension

Primary pulmonary hypertension disease is associated with a poor prognosis. Early diagnosis and the implementation of specific therapy are necessary to improve patients' prospects. In the near…
10. 3. 2021 Source: Pulmonary hypertension (CTEPH, PAH)
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Benefit of ixazomib in patients with relapsed/refractory multiple myeloma in routine clinical practice

The results of treating relapsed or refractory multiple myeloma in real-world routine clinical practice were published by a broad team of Czech experts in the journal BMC Cancer.
10. 3. 2021 Source: Hematologic Malignancies
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Diabetic Foot Syndrome: An Unpleasant Scare for Diabetics and Their Attending Doctors

Diabetic foot syndrome is a very serious complication of diabetes mellitus (DM). It often leads to destructive tissue damage distal to the ankle. Due to the complex therapy, it is advisable to focus…
8. 3. 2021 Source: Diabetes
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Pitfalls of Levothyroxine Replacement Therapy

Hypothyroidism (reduced function of the thyroid gland) affects approximately 1-2% of the population. Its prevalence increases with age and it is more common in women. Synthetic thyroid hormone…
8. 3. 2021 Source: Thyroid Disorders
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