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Relationship between Thyroid Gland Echogenicity and Its Function in Pediatric Patients with Hashimoto's Thyroiditis

22. 9. 2021 Source: Thyroid Disorders

Hashimoto's (chronic lymphocytic) thyroiditis is the most common cause of acquired hypothyroidism in both adults and pediatric patients in developed countries. The study presented below explored the relationship between thyroid gland (TG) echogenicity observed in ultrasound (US) examinations and its function in patients diagnosed with this condition.

Is the Quality of Life for Patients with Atrial Fibrillation and Heart Failure Comparable When Treated with Bisoprolol and Digoxin?

The British RATE-AF study, published in December 2020 in the JAMA journal, compared the impact on improving the quality of life in patients with permanent atrial fibrillation (AF) and symptoms of…
21. 9. 2021 Source: Cardiovascular Continuum
migrena, léčba silné migreny

Eletriptan as an effective and safe drug in acute migraine therapy

In the pharmacotherapy of acute migraine attacks, a pharmacologically diverse group of triptans is particularly used. The choice of the right antimigraine drug should be individualized, based on the…
20. 9. 2021 Source: Treatment of Severe Migraine
hemofilie_zkumavky

Individualized Prophylaxis with Achieving Higher Minimum Levels as a Possible Path to Optimal Treatment of Hemophilia A

Prophylactic administration of factor VIII (FVIII) concentrate is the standard of care for individuals with severe hemophilia A. Traditionally, the goal of prophylaxis has been to maintain minimum…
15. 9. 2021 Source: Hemophilia
Metamizol analgetika

Metamizole at a Glance and in Practice –⁠ Effective Non-Opioid Analgesic for All Ages

The regular webinar of the General Medicine Society of ČLS JEP this spring, besides addressing the current coronavirus situation, also focused on the issue and treatment of pain in its specialized…
15. 9. 2021 Source: Analgesia

Biosimilar Bevacizumab in Patients with Non-Small Cell Lung Cancer

Biosimilar drugs are essentially analogous to generics for biological medicines. The patent protection for the original bevacizumab product will expire in the European Union in 2022. Consequently,…
15. 9. 2021 Source: Oncological Treatment

Position of Generic Drugs in Oncology: What Are Their Main Advantages?

Generics –⁠ as is well known –⁠ are products containing the same active substance as the original medicinal product, which can enter the market after the patent protection of the original drug has…
15. 9. 2021 Source: Oncological Treatment
pohotovost

Monocyte Distribution Width as a New Indicator of Sepsis in High-Risk Patients

Most septic patients are first encountered in the emergency department, where sepsis detection is often delayed, partly due to a lack of effective biomarkers. The study presented below evaluated the…
13. 9. 2021 Source: Because
sepse

New Hematological Biomarker for Early Diagnosis of Sepsis

Sepsis is one of the leading causes of mortality and healthcare expenditure worldwide. Early diagnosis and treatment of septic conditions improve patient prognosis. However, the initial symptoms of…
13. 9. 2021 Source: Because
Kašel

Interstitial Lung Processes and Their Fibrotic Progression

Interstitial lung processes (ILPs) include more than 200 clinical units that share diffuse involvement of lung tissue and thus have similar clinical, radiological, and functional findings. However,…
10. 9. 2021 Source: Progressive Interstitial Pulmonary Processes
klinicka studie

Evaluation of Continuity of Care in Patients with mCRC –⁠ Baseline Characteristics of Participants in the PROMETCO Study

During this year's World Congress of the European Society for Medical Oncology (ESMO) on gastrointestinal malignancies, the baseline characteristics of participants in the ongoing PROMETCO study, which...
9. 9. 2021 Source: Treatment of Gastrointestinal Carcinomas
kongres doktorov

Trifluridine/tipiracil in Real Clinical Practice –⁠ Current Data from Spain

Trifluridine/tipiracil is indicated for the treatment of patients with refractory metastatic colorectal cancer (mCRC), where clinical studies have shown it extends overall survival (OS) and progression-free...
9. 9. 2021 Source: Treatment of Gastrointestinal Carcinomas
CLL prezentace Abbvie ilustrační

Evaluation of Treatment Response in CLL

The size of lymph nodes, liver, spleen, blood cell counts, systemic symptoms... Changes in these indicators provide clear information on whether the disease of chronic lymphocytic leukemia (CLL) has progressed,...
9. 9. 2021 Source: Chronic Lymphocytic Leukemia
plíce

Idiopathic Pulmonary Fibrosis: Can This Disease Be Named More Precisely?

Much about idiopathic pulmonary fibrosis (IPF) is still unknown. Some experts would like to reclassify this disease. What classification options are available? What would a focus on the "progressive…
9. 9. 2021 Source: Progressive Interstitial Pulmonary Processes
statistiky business grafy kancelář práce studie

Brigatinib in the Therapy of ALK-Positive NSCLC in Patients Refractory to Crizotinib Therapy –⁠ Results of the Final Analysis of Clinical Studies

Previously published results of clinical studies have shown that in patients refractory to crizotinib therapy, the administration of brigatinib led to a high rate of therapeutic response (systemic…
9. 9. 2021 Source: Non-Small Cell Lung Cancer
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