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Comparison of BEAM and TEAM Conditioning Regimens Before Autologous Hematopoietic Stem Cell Transplantation in the Treatment of Lymphomas
13. 6. 2023 Source: Oncological TreatmentAt the beginning of this year, one of the few studies comparing the most commonly used conditioning regimen before autologous hematopoietic stem cell transplantation (ASCT) in patients with lymphomas (BEAM) with a regimen containing thiotepa instead of carmustine (TEAM) was published.
Deficit dihydropyrimidine dehydrogenase and its association with 5-fluorouracil toxicity
Deficit dihydropyrimidine dehydrogenase (DPD) is a risk factor for severe toxicity of 5-fluorouracil (5-FU). Below, we summarize current knowledge regarding the identification of patients with…12. 6. 2023 Source: Genetics
Compression therapy in combination with surgical intervention in the treatment of venous leg ulcers and prevention of their recurrence
Compression therapy represents an important part of the treatment of venous leg ulcers; it also plays a role in preventing possible recurrences. The 4-year British ESCHAR study evaluated the impact…12. 6. 2023 Source: Wound Healing
Combination of Targeted Therapy with Chemo in 1st Line in Patients with Left-Sided wtRAS mCRC
The preferred targeted therapy added to the combination with standard chemotherapy (CHT) for left-sided metastatic colorectal cancer (mCRC) with non-mutated RAS oncogene should be an antibody against…9. 6. 2023 Source: Colorectal Cancer
Osteonecrosis of the Jaw Associated with Antiresorptive Pharmacotherapy in Oncological Patients
Antiresorptive pharmacotherapy in the form of bisphosphonates and denosumab is associated, according to current knowledge, with the risk of jaw osteonecrosis, especially following dental procedures…8. 6. 2023 Source: Prevention of Bone Events
Prediction of Hypocalcemia Risk in Patients Treated with Denosumab and Active Form of Vitamin D
According to new work by Japanese authors, it appears that the risk factors for the development of hypocalcemia in patients treated with denosumab and calcitriol (the active form of vitamin D) are…8. 6. 2023 Source: Prevention of Bone Events
Meta-analysis of Efficacy and Safety of Third-Generation Antiseizure Medications in Adjunctive Treatment of Focal Seizures in Adults with Epilepsy
Epilepsy treatment is primarily symptomatic, aimed at reducing seizure frequency. However, more than 50% of patients do not achieve seizure freedom with monotherapy. Below we summarize the results of…8. 6. 2023 Source: Epilepsy
How Does Cenobamate Compare with Third-Generation Anti-Seizure Medications in Terms of Cost-Effectiveness?
The main goal of epilepsy treatment is to achieve seizure freedom without unacceptable side effects of therapy. Despite the benefits of the latest generation of anti-seizure medications (ASMs),…8. 6. 2023 Source: Epilepsy
Comparison of the Risk of Interstitial Lung Disease in Patients with RA with Biological and Targeted Disease-Modifying Antirheumatic Therapy
The authors of a newly published study sought to answer whether the risk of developing interstitial lung disease in patients with rheumatoid arthritis (RA) is affected by the administration of…8. 6. 2023 Source: Arthritis
Effect of Azacitidine in the Treatment of Acute Myeloid Leukemia on Long-Term Patient Survival
The work cited below presents freshly updated results from the Quazar AML-001 study evaluating azacitidine (AZA) in the treatment of acute myeloid leukemia (AML), now with a median follow-up period…6. 6. 2023 Source: Acute Myeloid Leukemia
Oral Azacitidine Prolongs Survival of AML Patients Regardless of Measurable Residual Disease
Intensive chemotherapy for patients newly diagnosed with acute myeloid leukemia (AML) often achieves high remission rates, although these remissions are often only temporary. Consolidation therapy…6. 6. 2023 Source: Acute Myeloid Leukemia
Vaccination and ALEmtuzumab: ALE when?
When, why and against what should patients with multiple sclerosis treated with alemtuzumab be vaccinated? And is vaccination effective in this population?5. 6. 2023 Source: Multiple Sclerosis
Traveling with MS – Is Vaccination a Limitation?
What about the need for vaccination when traveling abroad? Which vaccines should you be cautious about? And how to time vaccination concerning disease activity and the individual medications used in…5. 6. 2023 Source: Multiple Sclerosis
Can Ketogenic Diet or Intermittent Fasting Help Patients with DM2 in Controlling Weight and Glycemia?
The foundation of managing type 2 diabetes mellitus (DM2) typically involves lifestyle adjustments, including dietary changes. Can intermittent fasting (IF) or the ketogenic diet (KD), popular…30. 5. 2023 Source: Modern Treatment of Diabetes
New Type of Fixation Allows Regular Limb Hygiene and Stay in Water
Conservative therapy for injuries and non-traumatic diseases of the musculoskeletal system is a daily reality in surgical and orthopedic clinics. An important part of treatment is limb fixation, most…26. 5. 2023 Source: proLékaře.czLogin#ADS_BOTTOM_SCRIPTS#Forgotten passwordEnter the email address that you registered with. We will send you instructions on how to set a new password.
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