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Ruka a prsty s psoriázou u psoriatické artrititidy

Comparison of Efficacy of Ixekizumab and Adalimumab in Patients with Psoriatic Arthritis and Moderate to Severe Psoriasis

9. 5. 2020 Source: Biological Treatment

Ixekizumab, a humanized monoclonal antibody against interleukin 17A (IL-17A), is approved in the Czech Republic for the treatment of active psoriatic arthritis (PsA) and moderate to severe plaque psoriasis. Its efficacy compared to adalimumab in PsA was evaluated in the head-to-head SPIRIT-H2H study. A post-hoc analysis of this study focusing on a subpopulation of patients with PsA and concurrent moderate to severe plaque psoriasis was presented at the Congress of the European Academy of Dermatology and Venereology (EADV) in October 2019 in…

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How to Improve Diabetic Adherence?

The dream of every doctor is a conscientious patient who follows the prescribed treatment and reports any potential problems in a timely manner. But where can such a patient be found?
7. 5. 2020 Source: Diabetes
žena rouška

Should patients with primary immunodeficiencies fear COVID-19 more than the general population?

The body fights the new SARS-CoV-2 virus, which causes COVID-19, in a similar way to other viral infections -⁠ by intensely engaging the immune system. But what if it's weakened?
7. 5. 2020 Source: Primary and Secondary Immunodeficiencies

Safety and Efficacy of Negative Pressure Therapy in Acute Infected Wounds

Negative Pressure Wound Therapy (NPWT) is a globally widespread wound care method. It involves creating a local negative pressure in the wound, with key benefits including moist wound healing in a closed...
4. 5. 2020 Source: Wound Healing
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Monotherapy with Bimatoprost in Patients with Glaucoma and Ocular Hypertension

Can monotherapy with bimatoprost be sufficiently effective in controlling intraocular pressure in non-responders to previous treatments? This is the question posed by British researchers in the…
4. 5. 2020 Source: Treatment of Glaucoma
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Effectiveness of Arginine in Tooth Cleaning Proven (Not Only) by Quantitative Light-Induced Fluorescence

There is no doubt about the benefits of toothpaste in daily dental care. Today, there are numerous studies proving that brushing without toothpaste does not have the same effectiveness as brushing…
4. 5. 2020 Source: Dental Caries
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Concise and Practical Recommendations for Optimal Care of Dental Prostheses

Millions of people around the world use full or partial dental prostheses. However, there are no standardized global procedures with guidelines on how to care for dental prostheses. Dentists and…
4. 5. 2020 Source: Optimal Care of Dentures
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Care for Dental Prostheses: What Did Clinical Study Results Reveal?

Dental prostheses are one of the most common solutions for missing teeth, especially in the elderly population. It is estimated that by 2050 up to 2 billion people will be aged 60 or older.…
4. 5. 2020 Source: Optimal Care of Dentures

New Era in Migraine Therapy

Migraine is the most common type of primary headache. It affects about 10% of the world population. Recurring migraine attacks significantly reduce quality of life. Therefore, research in…
4. 5. 2020 Source: Migraine
medicína žena břicho bolest žaludek stomie

Most Common Dermatoses Around the Stoma

The incidence of stomal complications ranges between 20 and 70%. One type of complication is dermatoses affecting the peristomal skin. These issues can occur in the early postoperative period, but…
4. 5. 2020 Source: Ostomy
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Principle of Slowed Wound Healing Due to Stress Revealed

There is no doubt that psychological stress significantly slows down the process of healing wounds. The principle of how this phenomenon occurs, however, has remained unexplained. Swiss scientists focused...
28. 4. 2020 Source: Wound Healing
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Pertuzumab significantly extends the life of patients with metastatic breast cancer

The final results of the CLEOPATRA clinical trial show that patients with HER2-positive metastatic breast cancer achieve 8-year overall survival of 37% with the targeted treatment combination of…
28. 4. 2020 Source: Breast Carcinoma
medicína žena břicho vaječníky menstruace karcinom bolest těhotenství

Maintenance treatment with oral olaparib in women with BRCA1/2 mutation and relapsed ovarian cancer

In a phase III study published in the journal Lancet Oncology, data on the effectiveness of olaparib in patients with ovarian cancer and BRCA1/2 mutation were evaluated. The poly(ADP-ribose)…
27. 4. 2020 Source: Ovarian and Breast Cancer
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The Benefit of Dabigatran Over Warfarin Is Greater in Patients with Atrial Fibrillation and Diabetes Than in Nondiabetics

As early as 2015, an analysis of the results of the RE-LY study in patients with atrial fibrillation showed that the reduction in absolute risk of embolic events with dabigatran compared to warfarin…
24. 4. 2020 Source: Anticoagulant Treatment
citrusy strom rostlina příroda zahrada pomeranče ovoce

Positive Effect of Diosmin on Venous Disease in Terms of Factors Responsible for Angiogenesis

A study published last year monitored the impact of diosmin on laboratory and clinical parameters related to the pathophysiology of chronic venous disease in patients.
23. 4. 2020 Source: Venous Insufficiency
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