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křečové žíly nohy žena medicína

Diosmin and Hesperidin: What Does Pharmacokinetics Show?

23. 4. 2020 Source: Venous Insufficiency

Flavonoids are plant-derived compounds that have a number of beneficial pharmacological effects. Among the most well-known flavonoids, alongside rutin, are diosmin and hesperidin, which are used as venotonics and vasoprotectives in chronic venous insufficiency (CVI).

Pacient_chemoterapie

Obinutuzumab and Early Progression of Patients with Previously Untreated Follicular Lymphoma −⁠ Analysis of Data from the GALLIUM Study

The GALLIUM study demonstrated longer progression-free survival (PFS) in patients with previously untreated follicular lymphoma (FL) treated with obinutuzumab compared to rituximab. The aim of the…
23. 4. 2020 Source: Non-Hodgkin Lymphomas and CLL
ledvina_ledviny

Impact of Dabigatran and Warfarin Treatment on the Risk of Acute Kidney Injury in Patients with Atrial Fibrillation

What clinical characteristics in patients with non-valvular atrial fibrillation may indicate a higher risk of acute kidney injury? Does the modality of anticoagulation therapy play a role in its…
23. 4. 2020 Source: Anticoagulant Treatment
konzultace léčby

High-Dose Cyclophosphamide in Hard-to-Treat Patients with B-NHL

For hard-to-treat patients with non-Hodgkin lymphoma, cyclophosphamide administered in one or two cycles can help bridge the period needed to obtain other effective treatments, as inferred from the…
23. 4. 2020 Source: Non-Hodgkin Lymphomas and CLL
:IMPORT-RN:

Boy with Hemophilia A with Inhibitor −⁠ Case Study with Voting

Presented by: Assoc. Prof. MUDr. Jan Blatný, Ph.D., Department of Pediatric Hematology, University Hospital Brno
22. 4. 2020 Source: Quality Life Even with Hemophilia
konzultace - geriatrický pacient

Efficacy of Combination Therapy for Chronic Lymphocytic Leukemia in Patients with Complex Karyotype

A complex karyotype (presence of ≥ 3 chromosomal abnormalities) is a negative prognostic marker in chronic lymphocytic leukemia (CLL). An analysis of the impact of complex karyotype on the efficacy…
22. 4. 2020 Source: Chronic Lymphocytic Leukemia
konference_kongres_přednáška_potlesk_medicína_lékaři

Role of Chemoimmunotherapy in the Era of Rapid Development of CLL Treatment Strategies and Emergence of New Drugs

In the context of the significant advancements in the field of immunotherapy and evidence of its efficacy in the treatment of chronic lymphocytic leukemia, it is pertinent to ask how this will…
22. 4. 2020 Source: Chronic Lymphocytic Leukemia
Guidelines

Recommendations for the diagnosis of ITP in adults and children according to ASH guidelines

The American Society of Hematology (ASH) guidelines from 2019 highlighted several important aspects in the diagnosis and treatment of ITP that have remained unchanged from the 2011 guidelines.
22. 4. 2020 Source: Immune Thrombocytopenia
Odběr krve_dětský pacient

Current ASH Guidelines on ITP Management 2019 –⁠ Recommendations for Newly Diagnosed ITP in Children

At the end of 2019, the American Society of Hematology (ASH) published current guidelines for immune thrombocytopenia (ITP), in which a panel of experts attempted to define evidence-based…
22. 4. 2020 Source: Immune Thrombocytopenia
Kloubní_náhrada_kyčel

Clinical Results of the Pinnacle Acetabular System: Data from the UK Joint Replacement Registry

The Pinnacle Acetabular System has been available on the market for nearly two decades. Since then, it has been implanted in numerous healthcare facilities worldwide. Clinical outcomes of the…
22. 4. 2020 Source: Large Joints
Svědící inkontinenční dermatitida

Incontinence Dermatitis -⁠ Common, Yet Often Overlooked Diagnosis

Incontinence dermatitis is an inflammatory skin reaction with a prevalence between 3 and 25%, caused by prolonged skin contact with urine or feces. It is classified among contact irritant dermatitis.…
21. 4. 2020 Source: Incontinence
PL_miminko_kojenec_dite

Through Obstacles to the Stars –⁠ Path to Developing a Healthy Gut Microbiota in Children: What Blocks It and What Helps?

The gut microbiota is acquired by an individual during the first 2 years of life. The main source is the mother’s microbiota. Obstacles to the formation of an adequate microbiota include…
21. 4. 2020 Source: GI, colic and microbiome
chemoterapie - pacient

FOLFOXIRI and Panitumumab in mCRC Treatment –⁠ Improvement in Treatment Response and Metastasis Resectability

For patients with metastatic colorectal cancer (mCRC) who are able to undergo intensive treatment, the FOLFOX (5-fluorouracil/leucovorin, oxaliplatin) or FOLFIRI (5-fluorouracil/leucovorin,…
21. 4. 2020 Source: Colorectal Cancer
konzultace - geriatrický pacient

Early Cytoreductive Treatment Delays Onset of Symptoms Associated with Metastatic Colorectal Carcinoma

Managing symptoms associated with advanced cancer has a significant impact on patients' quality of life and influences decisions about appropriate therapy for an individual patient. An international…
21. 4. 2020 Source: Colorectal Cancer
diabetes_cukrovka_medicína

Itoprid helps diabetics with reduced gastrointestinal motility improve diabetes control

The prokinetic itoprid led not only to the alleviation of gastroparesis symptoms and an improvement in quality of life in a prospective multicenter observational study on patients with diabetes and…
21. 4. 2020 Source: Gastrointestinal Treatment
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