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News Administration of Low-Molecular-Weight Heparin After Hemorrhagic Stroke: What Is the Appropriate Timing?

Hemorrhagic stroke (HS) is a condition that raises doubts and concerns about anticoagulation. Is early prevention of thromboembolic complications appropriate?

Source: Thromboprophylaxis 30. 9. 2021

News Biocompatibility of 3D Printed Materials –⁠ Their Comparison, Legislation, and Practice

Printing three-dimensional (3D) objects brings new possibilities for producing personalized implants, prosthetics, and other medical devices in healthcare. One area where this technology can improve current practice is the printing of tracheostomy tubes for use in patients after laryngectomy. However, it is crucial to ensure the biocompatibility of the materials used for printing. In November 2023, a study comparing 3D printer materials in terms of their susceptibility to the growth of bacterial biofilms from Staphylococcus aureus was published in the journal 3D Printing in Medicine.

Source: 27. 3. 2024

News New Therapeutic Options in Light of Current Knowledge on the Pathogenesis of Atopic Dermatitis

Atopic dermatitis (AD) is a chronic inflammatory skin disease characterized by intense itching and recurrent eczematous lesions. AD is diagnosed in 2 out of 10 children and often persists into adulthood. In developed countries, it is the most common skin disease with a lifetime prevalence exceeding 15%. However, it is also very diverse due to a wide range of clinical phenotypes reflecting various pathophysiological mechanisms and interactions between genetics, the immune system, and the environment. So, what have we learned about atopic dermatitis from recent research, and how has this translated into advances in its treatment?

Source: Biological Treatment 14. 11. 2022

News Romiplostim brings benefit also to patients with ITP lasting less than 1 year

What is the role of second-line therapy, in this case romiplostim, in the management of adult ITP patients who have not yet reached the chronic phase of the disease?

Source: Immune Thrombocytopenia 21. 11. 2023

News Valproate for Acute Mania: Is Practice Really Evidence-Based and Recommended?

Authors from the University of Western Ontario conducted an audit in an acute psychiatric intake unit to determine whether the prescription of valproate there corresponded to evidence-based recommendations.

Source: Bipolar Disorder 18. 2. 2020

News Identification of patients with advanced Parkinson's disease suitable for device-aided therapy (DAT)

To properly implement device-aided therapy in Parkinson's disease (PD) management, it is essential to timely identify patients in advanced stages of the disease who might benefit from this therapeutic approach. We summarize the useful tools that doctors can use to find these patients.

Source: Parkinson's Disease 14. 9. 2023

News Meta-Analysis of the Results of Studies Comparing the Effectiveness of Manual and Sonic Toothbrushes

Brushing teeth is a fundamental means of maintaining good oral hygiene. While many people still rely on using manual toothbrushes, brushing with electric toothbrushes has also gradually gained significant popularity. Several studies comparing the effectiveness and gentleness of these two approaches have been conducted in the past, followed by a meta-analysis of their results.

Source: Dental Care 21. 4. 2023

News 6 Possible Benefits of Adding Empagliflozin to Metformin

Currently, there is intense discussion about the advantages of sodium-glucose co-transporter 2 inhibitors (SGLT2i, also known as gliflozins) in terms of their cardio and nephroprotective properties. Below, we summarize the proven beneficial effects specifically associated with adding empagliflozin to metformin and mention the indications for empagliflozin, which are reimbursed.

Source: Diabetes 14. 11. 2022

News Hybrid Cooperative Complexes in the Treatment of Osteoarthritis

Intra-articular application of corticosteroids and hyaluronic acid is part of the treatment of osteoarthritis (OA) in patients for whom oral or topical treatment does not provide sufficient response. The following text addresses the lubricating and protective properties of synovial fluid and the related choice of appropriate intra-articular viscosupplementation, with emphasis on innovative molecules with high concentrations of hyaluronic acid and low viscosity.

Source: Pain Management 18. 6. 2024

Články časopisu Current results of colorectal cancer screening and potential value of colon capsule endoscopy in the Czech Republic

Author of the article: O. Ngo, R. Chloupková, Suchánek Š., Zavoral M., Dušek L., O. Májek Source: Gastroenterologie a hepatologie | 5/2019 31. 10. 2019

News Primum non nocere applies not only in medicine: an ecological look at inhalers

According to estimates from the World Health Organization (WHO), around 65 million people worldwide suffer from mild to moderate forms of chronic obstructive pulmonary disease (COPD). The cornerstone of therapy is the inhalation administration of bronchodilator drugs. While there is no doubt that this therapy helps patients, what impact do the propellants in inhalation systems have on the global climate? And is there a sensible solution to this problem?

Source: COPD 25. 5. 2020

News Study COPDGene Redefines Diagnostic Criteria of Chronic Obstructive Pulmonary Disease

Chronic obstructive pulmonary disease ranks among the top causes of morbidity and mortality worldwide. Current diagnostic criteria for the disease are based exclusively on spirometric examination. Increasing evidence, however, suggests that a significant number of patients show signs of chronic obstructive pulmonary disease without pathological findings on spirometry. The analysis of the COPDGene study thus proposes expanding the diagnostic criteria to include additional parameters.

Source: COPD 28. 5. 2020

News What impact do the symptoms of primary biliary cholangitis have on the patient and their quality of life

Primary biliary cholangitis (PBC) is a serious chronic cholestatic autoimmune liver disease that predominantly affects middle-aged women and can lead to end-stage liver failure and the need for transplantation. Several studies published this year show a reduction in the quality of life of patients with this disease due to its accompanying symptoms.

Source: Primary Biliary Cholangitis 12. 10. 2020

News Complex Impacts of Obesity on the Brains of People with Psychiatric Disorders

Obesity in individuals with bipolar disorder or schizophrenia is closely linked not only to higher mortality but also to worse progression of the psychiatric illness, lower response to psychiatric treatment, more frequent fatal outcomes (suicide), deterioration in cognitive functions, and structural brain damage. In his lecture at the XIV Congress of the Psychiatric Society of the Czech Medical Association J.E. Purkyně in Mikulov in June 2022, Professor Tomáš Hájek from Dalhousie University in Halifax, Canada, focused on these connections.

Source: Modern Treatment of Schizophrenia 18. 8. 2022

News One Step Closer to Understanding the Placebo Effect in Pain Treatment

Neuroscientists from the USA appear to have advanced our understanding of the placebo effect in pain relief. Their findings, recently published in Nature, open the possibility of influencing the described pain control pathway using drugs or neurostimulation.

Source: 12. 12. 2024