Interdisciplinary recommendations for thrombophilia testing

Czech version

Authors: E. Drbohlavová ¹; J. Gumulec ²; A. Buliková ³; P. Ďulíček ⁴; J. Hirmerová ⁵; R. Malý ⁶; E. Zápotocká ⁷; J. Blatný ⁸; J. Václavík ⁹; P. Kessler ¹⁰
Published in: Transfuze Hematol. dnes,31, 2025, No. 2, p. 132-136.
Category:
doi: https://doi.org/10.48095/cctahd2025prolekare.cz9

Overview

In this interdisciplinary consensus of four medical societies dealing with thrombophilic disorders, we summarize the rules of diagnosis and care of patients with congenital or acquired thrombophilias, i.e. factors increasing the risk of venous thromboembolic disease. The primary goal is to standardize the care of these patients with respect to the rules of evidence-based medicine. The recommendations imply under which circumstances, in which clinical situations, for which patients and which tests it is useful to investigate which thrombophilias and when not. Despite the long history and very good availability of diagnostic tests for individual thrombophilias, no similar recommendation has been published in the Czech Republic.

Keywords:

Venous thromboembolism – arterial thrombosis – congenital and acquired thrombophilias – JAK2 mutation and PNH clone testing

Sources

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Do redakce doručeno dne: 23. 4. 2025.

Přijato dne: 9. 5. 2025.

Eva Drbohlavová

Oddělení klinické hematologie

Krajské nemocnice Liberec a. s.

Baarova 526 /15

460 01 Liberec

e-mail: eva.drbohlavova@nemlib.cz