Authors: Z. Stašková 1,2; Š. Ožanová 1,2; K. Balošáková 1,2; J. Václavík 1,2 Authors‘ workplace: Interní a kardiologická klinika FN Ostrava 1; Katedra interních oborů, LF OU, Ostrava 2 Published in: Transfuze Hematol. dnes,31, 2025, No. 2, p. 103-107. Category: Case Reports doi: https://doi.org/10.48095/cctahd2025prolekare.cz10
Thrombotic microangiopathies represent a heterogeneous group of diseases of various aetiology, whose common feature is damage to the endothelium of small blood vessels. Typical laboratory findings include thrombocytopenia and microangiopathic haemolytic anaemia, along with signs of organ damage (most commonly affecting the kidneys). In the differential diagnosis, it is necessary to differentiate, among other conditions, autoimmune diseases with multi-organ failure. This case report presents a case of the young woman who developed multi-organ failure in the early postpartum period. For this patient, it was the first manifestation of systemic lupus erythematosus. Despite prompt diagnosis and treatment, the course of hospitalization was complicated – both due to the underlying disease and due to severe infections, that required adjustments to her immunosuppressive therapy. The patient was discharged to outpatient care after nearly four months of intensive treatment, and her condition continues to improve.
Systemic lupus erythematosus – thrombotic microangiopathies – multi-organ failure
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Podíl autorů na přípravě rukopisu
ZS – napsání rukopisu, léčba nemocné
KB – léčba nemocné
ŠO – léčba nemocné, kontrola, revize rukopisu
JV – kontrola, revize rukopisu
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Do redakce doručeno dne: 27. 3. 2025.
Přijato po recenzi dne: 21. 4. 2025.
MUDr. Stašková Zuzana
Interní a kardiologická klinika
FN Ostrava
17. listopadu 1790/5
708 52 Ostrava-Poruba
e-mail: zuzana.staskova@fno.cz
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