Analysis of Circadian Rhythm Influence to Heart Rate Turbulence in Patients Post Myocardial Infarction with Left Ventricular Dysfunction

Authors: M. Sepši 1;  M. Kozák 1;  P. Trčka 1;  L. Křivan 1;  J. Vlašínová 1;  M. Kýr 2
Authors‘ workplace: Interní kardiologická klinika FN, Brno 1;  Institut biostatistiky a analýz MU, Brno 2
Published in: Čas. Lék. čes. 2007; 146: 712-717
Category: Original Article


Some study reported circadian occurence of sudden cardiac death, ventricle ectopic activity, acute coronary syndromes and heart rate variability. Heart rate turbulence (HRT) is one of a new markers of noninvasive stratification of sudden cardiac death. 

Methods and Results.
We have evaluated HRT in 120 consecutive patiens post myocardial infarction in mean age 62,7±12,4 years (90 M, 30 W), indicated for ecg Holter monitoring with LVEF 0,45±0,12 in 2hours interval during 24 hours. We have analysed circadian variation of the HRT. 

The statistically significant circadian patterns were found in turbulence slope parameter of HRT. No significant changes for turbulence onset parameter were described. 

Key words:
heart rate turbulence, sudden cardiac death, good left ventricle function.

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