Cutaneous Complications of the Idiopathic Inflammatory Bowel Disease

Authors: P. Chalupná;  M. Lukáš;  S. Adamec;  R. Šroubková;  M. Antošová;  S. Romaniv
Authors‘ workplace: Gastroenterologické centrum IV. interní kliniky 1. LF UK a VFN, Praha
Published in: Čas. Lék. čes. 2002; : 715-717


A 29-year-old male patient with the anamnesis of inflammatory bowel disease and Grave-Basedowov disease washospitalized because of rapidly spreading skin defect with affected muscle on the left shin. This skin defect appearedafter the significant decreasing of corticoids. The small skin trauma preceded the pyoderma gangrenosum. First theskin diseasewas not right diagnosed and patient was cured by the excision of the defect. It caused tissue disintegration,muscle necrosis and extension of the defect. The whole leg was endangered. Patient was cured with corticoids andcyclosporin A after the right diagnosis. The defect healed and laboratory inflammatory markers decreased. Theimmunosupresive therapy was changed to azathioprin, the corticoid therapy was interrupted. After three months thedefect was healed.

Key words:
inflammatory bowel disease – pyoderma gangrenosum – cyclosporin A.

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