Autoantibodies in the Pathogenesis and Diagnosis of Insulin-dependent Diabetes Mellitus
; J. Škrha
III. interní klinika 1. LF UK a VFN, Praha
Čas. Lék. čes. 1999; : 268-271
Insulin-dependent diabetes mellitus is considered an autoimmune disease. The immune response is targeted onautoantigens of B-cells of the islets of Langerhans. The most important autoantigens are glutamic acid decarboxylase,protein tyrosine phosphatase and insulin. Despite the fact that their role in the pathogenesis of insulin-dependentdiabetes mellitus is not clear, they are used in diagnosis and can identify subjects at high risk for the developmentof the disease.
insulin-dependent diabetes mellitus, autoimmune disease, autoantibodies, glutamate decarboxylase,tyrosine phosphatase.
Full text is not available online.
If interested in a scan of this journal, contact NTO ČLS JEP
Allergology and clinical immunology
Dermatology & STDs