Authors: V. Teplan; R. Poledne 1; O. Schück; M. Štollová; O. Mengerová; Š. Vítko 2 Authors‘ workplace: Klinika nefrologie TC IKEM, Praha Laboratoř pro výzkum aterosklerózy, Kardiocentrum IKEM, Praha 2 Transplantcentrum IKEM, Praha Published in: Čas. Lék. čes. 1999; : 111-115 Category:
Background. Atherosclerosis of the blood vessels is the most frequent cause of morbidity and mortality of patientsafter transplantation of the kidneys with a long-term function of the graft. It is assumed that the most significant riskfactor for its development is secondary hyperlipoproteinaemia (HLP). In the development of HLP a number of factorsmay participate (chronic renal insufficiency, proteinuria, immunosuppressive treatment, diet, increment of bodyweight, age, genetic factors).The objective of the investigation was to follow changes of the lipid spectrum after renal transplantation andevaluate the impact of different factors which participate in these changes.Methods and Results. The authors investigated in a retrospective metabolic study for a period of 18 months a totalof 348 patients after the first cadaverous kidney transplantation. They compared the findings in 34 patients (groupI) who had throughout the investigation period a total cholesterol of
Key words: renal transplantation, atherosclerosis, hyperlipoproteinaemia, diet, age, immunosuppression.
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