Hepatorenal syndrome – pathophysiology, diagnosis and treatment

Authors: Vladimír Hrabovský;  Alice Mendlová;  Terezie Vavříčková
Authors‘ workplace: Interní klinika LF OU a FN Ostrava, přednosta doc. MUDr. Arnošt Martínek, CSc.
Published in: Vnitř Lék 2015; 61(7-8): 649-654
Category: Reviews


Hepatorenal syndrome (HRS) is a life-treating complication of liver diseases. This functional kidney impairment is classified into acute (type I) and chronic (type II) types and is connected with high mortality. Treatment options are limited, but administration of vasoconstrictors (terlipressin), albumin and portosystemic shunt may improve their prognosis. Liver transplantation is the most effective method for these patients. Authors want to present recent data relating to HRS, including therapeutic recommendations.

Key words:
albumin – hepatorenal syndrome – liver cirrhosis – terlipressin


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