The FEVER (Felodipine EVEnt Reduction) trial; a randomised, double-blind, placebo-controlled trial in Chinese hypertensive patients


Authors: A. Mokráček 1;  J. Špatenka 2;  M. Šulda 1;  F. Toušek 1;  H. Pospíšilová 1;  M. Vambera 1;  M. Šetina 2;  L. Pešl 1
Authors‘ workplace: Kardiocentrum Nemocnice České Budějovice, ředitel MUDr. Ladislav Pešl 1;  Transplantační centrum a oddělení kardiovaskulární chirurgie Kardiovaskulárního centra FN Motol, Praha, přednosta prim. MUDr. Jaroslav Špatenka, CSc. 2
Published in: Vnitř Lék 2007; 53(1): 54-62
Category: Reviews

Overview

After 40 years of heart valve prostheses intensive development ideal valve substitute still does not exist. Aortic allograft represents one alternative which could be used for aortic and/or pulmonary valve replacement. This type of biological heart valve prosthesis is being currently discussed from the point of view of Tissue Banking, as well as from clinical aspects – e.g. surgical implantation technique and long term results. Live issue remains particularly the aortic allograft implantation into the aortic position. The authors discuss the aortic allograft role in the aortic valve infectious endocarditis treatment, which was widespread worldwide and accepted. Aortic allograft implantation is considered as a method of choice in that particular indication, especially in prosthetic aortic valve endocarditis and in left ventricle outlet tract destruction cases. The method is considered to be more technically demanding than routine heart valve surgery (heart valve replacement by means of mechanical or commercial biological prostheses), but literary and authors own experience in that particular group of patients looks encouraging. Aortic allografts permanent supply in our country is secured.

Key words:
infectious endocarditis - aortic valve - aortic allograft - aortic homograft


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Diabetology Endocrinology Internal medicine

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