Pneumology problems of patients with diabetes mellitus


Authors: H. Bartáková;  L. Brunerová;  M. Anděl
Authors‘ workplace: II. interní klinika 3. lékařské fakulty UK a FN Královské Vinohrady, Praha, přednosta prof. MUDr. Michal Anděl, CSc.
Published in: Vnitř Lék 2005; 51(5): 566-577
Category: Reviews

Overview

Diabetes mellitus is a system disease, which can result in a multiorgan dysfunction. The most serious pulmonary complications of diabetes mellitus are the lower respiratory tract infections developing under immunity dysfunction and under structural and functional pulmonary or extrapulmonary changes. Non–cardiogenic edema can occur as a complication of acute diabetic status such as ketoacidosis or hypoglycemic coma. Immunity dysfunction in diabetic patients seems to have even more complicated consequences according to a previously published study showing lower incidence of ARDS in diabetic patients with septic shock compared to nondiabetics. The question is whether the immunity dysfunction, particularly that of polymorphonuclear cells impairing the resistance against infections, does not reduce the risk of ARDS development.

Key words:
diabetes mellitus – pulmonary function – immunity dysfunction – pneumonia – ARDS


Sources

1. Annese V, Bassoti G. Gastrointestinal motor dysfunction, symptoms and neuropathy in NIDDM. J Clin Gastroenterol 1999; 29: 171–177.

2. Bartáková H, Anděl M. Plicní komplikace diabetes mellitus. Diabetologie, metabolismus, endokrinologie, výživa 1998; 4: 173–179.

3. Bashar M, Alcabes P, Rom WN et al. Increased incidence of multidrug-resistant tuberculosis in diabetic patients on the Bellevue Chest Service 1987–1997. Chest 2001; 120(5): 1514–1519.

4. Baum GL, Wolinsky E. Textbook of pulmonary diseases. Vol. II. Boston: Little Brown 1994: 1649–1652.

5. Behera D, Das S, Dash RJ et al. Cough reflex in diabetes mellitus with and without autonomic neuropathy. Respiration 1995; 62(5): 263–268.

6. Benbassat CA, Stern E, Karmer M et al. Pulmonary function in patients with diabetes mellitus. Am J Med Sci 2001; 322(3): 127–132.

7. Berger HW, Granada MG. Lower lung field tuberculosis. Chest 1974; 65(5): 522–526.

8. Brandstetter LD, Tamarin FM. Ocult mucous airway obstruction in diabetic ketoacidosis. Chest 1987; 91: 575–578.

9. Brownlee M. Glycation products and the pathogenesis of diabetic complications. Diabetes care 1992; 15: 1835–1843.

10. Brownlee M, Vlassara H, Cerami A. Nonenymatic glycosylation and the pathogenesis of diabetic complications. Annals of Internal Medicine 1984; 101: 527–537.

11. Bryan C, Reynolds K. Bacteremic nosocomial pneumonia. Am Rev Respir Dis 1984; 129: 668–671.

12. Carton JA, Maradona JA, Nuno FJ et al. Diabetes mellitus and bacteraemia: A comparative study between diabetic and non–diabetic patients. Eur J Med 1992; 1: 281–287.

13. Dahl-Jorgensen, K.: Diabetic microangiopathy. Acta Paediatr 1998; 425 (Suppl):, 31–34.

14. Delamaire M, Maugendre D, Moreno M et al. Impaired leukocyte functions in diabetic patients. Diabetic Medicine 1997; 14: 29–34.

15. Djavani M, Yenice S, Kirkali G et al. Interstitial collagens isolated from lung of rabbits with alloxan-induced diabetes mellitus. Biochemical Society Transactions 1993; 21: 274.

16. Farina J, Furio V, Fernandez-Acenero MJ et al. Nodular fibrosis of the lung in diabetes mellitus. Virchows Arch 1995; 427: 61–63.

17. Fein AM, Calalang–Colucci MG et al. Acute lung injury and acute respiratory distress syndrome in sepsis and septic shock. Critical Care Clinics 2000; 16(2): 289–317.

18. Frank JA, Nuckton TJ, Matthay MA. Diabetes mellitus: A negative predictor for the development of acute respiratory distress syndrome from septic shock. Critical Care Medicine 2000; 28(7): 2645–2646.

19. Fuso L, Cotroneo P, Basso S et al. Postural variations of pulmonary diffusing capacity in insulin-dependent diabetes mellitus. Chest 1986; 110(4): 1009–1013.

20. Geerlings SE, Hoepelman AIM. Immune dysfunction in patients with diabetes mellitus. Immunology and Medical Microbiology 1999; 26: 259–265.

21. Glass E, Stewart J, Matthews D et al. Impairment of monocyte „lectin-like“ receptor activity in Type I (insulin-dependent) diabetic patients. Diabetologia 1987; 30: 228–231.

22. Groeneveld AB. Vascular pharmacology of acute lung injury and acute respiratory distress syndrome. Vascul Pharmacol 2002; 39(4–5): 247–256.

23. Guazzi M, Oreglia I, Guazzi MD. Insulin improves alveolar-capillary membrane gas conductance in type 2 diabetes. Diabetes Care 2002; 25(10): 1802–1806.

24. Huang S. Asthma and diabetes. The Lancet 1999; 354: 515.

25. Christian JL, Brun-Buisson M, Bonnet F et al. Recurrent high-permeability pulmonary edema associated with diabetic ketoacidosis. Crit Care Med 1985; 13(1): 55–57.

26. Ingbar DH. Mechanism of repair and remodeling following acute lung injury. Clinics in Chest Medicine 2000; 21(3): 589–616.

27. Jian R. Disorders of gastric emptying. Presse Med 1992; 21: 1072–1078.

28. Kaneki T, Koyama S, Wada S et al. Acute pulmonary edema caused by accidental aspiration of sweetened water in two cases of diabetes mellitus. Intern Med 1998; 37: 969–972.

29. Karačunskij MA, Panasek IA, Filippov VP. Legočnaja mikroangiopatia pri tuberkuleze legkich, razvivšemsia u bolnych sacharnym diabetom. Probl Tuberk 1996; 6: 50–52.

30. Katz S, Klein B, Elian I. Phagocytic activity of monocytes from diabetic patients. Diabetes Care 1983; 6: 479–482.

31. Kinekawa F, Kubo F, Matsuda K et al. Relationship between esophageal dysfunction and neuropathy in diabetic patients. Am J Gastroenterol 2001; 96: 2026–2032.

32. Koziel H, Koziel MJ. Pulmonary complications of diabetes mellitus. Infectious Disease Clinics of North America 1995; 9: 65–90.

33. Krausová Z, Pavlík Z, Anděl M et al. Sérové hladiny a močové vylučování zinku u nemocných s inzulin dependentním diabetem. Časopis lékařů českých 1990; 129: 945–949.

34. Lang S, Thorsteinsson B, Nerup J et al. Diabetes mellitus in cystic fibrosis: effect of insulin therapy on lung function and infections. Acta Pediatr 1992; 151: 684–687.

35. Lipsky BA, Pecoraro RE, Chen MS. Factors affecting staphylococcal colonization among NIDDM outpatients. Diabetes Care 1987; 10: 483–486.

36. Lluch I, Ascaso JF, Mora F et al. Gastroesophageal reflux in diabetes mellitus. Am J Gastroenterol 1999; 94: 919–924.

37. Loukides S, Polyzogopoulos D. The effect of diabetes mellitus on the outcome of patients with chronic obstructive pulmonary disease exacerbated due to respiratory infections. Respiration 1996; 63: 170–173.

38. Marhoffer W, Stein M, Maeser E et al. Impairment of polymorphonuclear leukocyte function and metabolic control of diabetes. Diabetes Care 1992; 15: 256–260.

39. Marinos E. Changing concepts of nutrient requirements in disease: implications of artificial support. Lancet 1995; 345: 1279–1284.

40. Marvisi M, Marani G, Brianti M et al. Pulmonary complications in diabetes mellitus. Recenti Prog Med 1996; 87(12): 623–627.

41. McMahon MM, Bistrian BR. Host defenses and susceptibility of infection in patients with diabetes mellitus. Infectious Disesase Clinics of North America 1995; 9: 1–9.

42. Moran A, Doherty L, Wang X et al. Abnormal glucose metabolism in cystic fibrosis. J. Pediatr. 1998; 133(1): 10–16.

43. Morris JT, Seaworth BJ, Mc Alister CK. Pulmonary tuberculosis in diabetics. Chest 1992; 102: 539–541.

44. Moss M, Guidot DM, Steiberg KP et al. Diabetic patients have a decreased incidence of acute respiratory distress syndrome. Crit Care Med 2000; 28(7): 2187–2192.

45. Paradisi F, Corti G, Messeri D. Antistaphylococcal (MSSA, MRSA, MSSE, MRSE) antibiotics. Medical Clinics of North America 2001; 1(85): 1–17.

46. Piccioni M, Manfrini S. Bronchial responsiveness to methacholine in insulin–dependent diabetic patients with autonomic neuropathy. Chest 1994: 105(2); 644–645.

47. Ravel A. Clinical Laboratory Medicine. 6th ed. Philadephia: Mosby-Year Book 1995.

48. Sandler M, Bunn AE, Stewart RI. Cross section study of pulmonary function in patients with insulin-dependent diabetes mellitus. Am Rev Respir Dis 1987; 135: 223–229.

49. Santos e Fonseca CM, Manco JC, Gallo Junior L et al. Cholinergic bronchomotor tone and airway caliber in insulin-dependent diabetes mellitus. Chest 1992; 101(4): 1038–1043.

50. Shernthaner G, Haber P, Kummer F et al. Lung elasticity in juvenile onset diabetes mellitus. Am Rev Resp Dis 1977; 116: 544–554.

51. Schleider ED, Wagner E, Uerlich AG. Increased accumulation of the glycoxidation product N (epsilon) – (carboxymethyl) lysine in tissues in diabetes and aging. J Clin Invest 1997; 99(3): 457–468.

52. Schnack C, Festa A, Schwarzmaier D et al. Pulmonary dysfunction in type 1 diabetes in relation to metabolic longterm control and to incipient diabetic nephropathy. Nephron 1996; 74: 395–400.

53. Schnapf BM, Banks RA, Silverstein JH et al. Pulmonary function in insulindependent diabetes mellitus with limited joint mobility. Am Rev Respir Dis 1984; 130(5): 930–932.

54. Suga T, Sugiyama Y, Kitamura S. Clinical study of patients with idiopathic interstitial pneumonia accompanied by diabetes mellitus. Nippon Kyobu Shikkan Gakkai Zashi 1994; 32(12): 1131–1135.

55. Theodore J, Robin ED. Pathogenesis of neurogenic pulmonary oedema. The Lancet 1975; 18: 749–751.

56. Vlassara H. Advanced glycation endproducts and atherosclerosis. Annals of Medicine 1996; 28: 419–426.

57. Wang CH, Yu CT, Lin HC et al. Hypodense alveolar macrophages in patients with diabetes mellitus and active pulmonary tuberculosis. Tuber Lung Dis 1999; 79(4): 235–242.

58. Wanke T, Formanek D. Mechanical load in the inspiration muscles during exercise hyperpnoe in patients with 1. type diabetes mellitus. Diabetologia 1992; 35: 425–428.

59. Wanke T, Abrahamian H, Lahrmann H et al. No effect of naloxone on ventilatory response to progressive hypercapnia in IDDM patients. Diabetes 1993; 42: 282–287.

60. Wanke T, Paternostro–Sluga T, Grisold W et al. Phrenic nerve function in type 1 diabetic patients with diaphragm weakness and peripheral neuropathy. Respiration 1992; 59: 233–237.

61. Weir DC, Jennings PE, Hendy ML et al. Transfer factor for carbon monoxide in patients with diabetes with and without microangiopathy. Thorax 1988; 43: 725–726.

62. Woodhead M, Mac Farlane J, McCracken J. Prospective study of the aetiology and outcome of pneumonia in the community. Lancet 1987; 1: 671–674.

Labels
Diabetology Endocrinology Internal medicine

Article was published in

Internal Medicine

Issue 5

2005 Issue 5

Most read in this issue
Login
Forgotten password

Don‘t have an account?  Create new account

Forgotten password

Enter the email address that you registered with. We will send you instructions on how to set a new password.

Login

Don‘t have an account?  Create new account