Cause of clinical manifestations of chronic venous insufficiency in patients with overweight and obesity


Authors: D. Musil 1;  J. Herman 2
Authors‘ workplace: Nestátní interní a cévní ambulance, II. poliklinika, Olomouc 1;  II. chirurgická klinika Lékařské fakulty UP a FN Olomouc, přednosta prof. MUDr. Miloslav Duda, DrSc. 2
Published in: Vnitř Lék 2005; 51(5): 523-528
Category: Original Contributions

Overview

The aim of the paper was to answer the question to what degree clinical manifestations of chronic venous insufficiency in patients with overweight and obesity have connection with increased body weight, possibly with its various complications, and to what degree they are based on underlying primary infliction of lower limb venous system. Population consisted of 100 patients ((78 females a 22 males) with manifestations of chronic venous insufficiency (C1–C6 according to CEAP). Nutrition status of the patients was evaluated based on BMI: control group with BMI ≥ 20–25 kg/m2 (n = 49), monitored group with BMI ≥ 26 kg/m2 (n = 43) was divided in overweight patients (BMI ≥ 26–29 kg/m2) and obese patients (BMI ≥ 30 kg/m2). In control group of patients with BMI ≥ 20–25 kg/m2 we demonstrated primary infliction of venous wall (67.3%) as a main cause of clinical manifestations of chronic venous insufficiency, which was exhibited by reflux in superficial venous system and supported by positive family history (77.6%) and high correlation between positive family history and the infliction of superficial veins (67.3%). In monitored group with BMI ≥ 26 kg/m2 and BMI ≥ 30 kg/m2) causes of clinical manifestations of chronic venous insufficiency can be divided at least into three groups: 1. primary infliction of venous wall (55% verweight patients, 20.8% obese patients) supported by positive family history, 2. obesity as a primary cause of symptoms of chronic venous insufficiency, 3. obesity as a main risk factor of various diseases which can lead to secondary posttraumatic or postthrombotic infliction of lower limb venous system.

Key words:
chronic venous insufficiency – duplex sonography – risk factors – overweight – obesity – BMI – heredity – reflux


Sources

1. Agus GB et al. Guidelines on compression therapy. Acta Phlebologica 2001; 2(Suppl 1): 1–24.

2. Brand FN et al. The epidemiology of varicose veins: The Framingham Study. Am J Prev Med 1998; 4: 96–101.

3. Fowkes FG, Evans CJ, Lee AJ. Prevalence and risk factors of chronic venous insufficiency. Angiology 2001; 52(Suppl 1): S5–S15.

4. Jawien A. The influence of enviromental factors in chronic venous insufficiency. Angiology 2003; 54(Suppl 1): S19–S31.

5. Lacroix P, Abovans V, Preux P et al. Epidemiology of venous insufficiency in an occupational population. Int Angiol 2003; 22(2): 172–176.

6. Musil D, Herman J. Anatomické a hemodynamické změny na žilním řečišti dolních končetinách postižených chronickou žilní insuficiencí. Vnitř Lék 2003; 49(8): 610–617.

7. Padberg F, Cerveira JJ, Lal BK et al. Does severe venous insufficiency have a different etiology in the morbidly obese? Is it venous? J Vasc Surg 2003; 37(1): 79–85.

8. Sadick NS. Predisposing factors of varicose veins and teleangiectatic leg veins. J Dermatol Surg Oncol 1992; 18: 883–886.

Labels
Diabetology Endocrinology Internal medicine

Article was published in

Internal Medicine

Issue 5

2005 Issue 5

Most read in this issue
Login
Forgotten password

Don‘t have an account?  Create new account

Forgotten password

Enter the email address that you registered with. We will send you instructions on how to set a new password.

Login

Don‘t have an account?  Create new account