#PAGE_PARAMS# #ADS_HEAD_SCRIPTS# #MICRODATA#

Loneliness in the aetiology of somatic illnesses


Authors: R. Ptáček 1;  H. Kuželová 1,2;  M. Vráblík 3
Authors‘ workplace: 1. lékařská fakulta a Všeobecná fakultní nemocnice v Praze ;  Psychiatrická klinika Přednosta: prof. MUDr. Jiří Raboch, DrSc. 1;  Ústav lékařské biologie a genetiky 2. LF UK Přednosta: prof. MUDr. Milan Macek, DrSc. 2;  3. interní klinika 1. LF UK a VFN Přednosta: prof. MUDr. Štěpán Svačina, DrSc., MBA 3
Published in: Prakt. Lék. 2011; 91(6): 325-327
Category: Reviews

Overview

Loneliness is not only a psychological and social problem that affects an indiviual´s psyche, it is also a medical problem. Loneliness is a state similar to long-term stress, where the organism is exhausted. People who are lonely have sleep problems and report worse quality of rest, and it is thought they have an increased incidence of a number of somatic diseases. Many of the diseases result from decreased immunity, but the major problem in lonely people is a high incidence of cardiovascular diseases.

Key words:
loneliness, social isolation, somatic illnesses, cardiovascular disorders.


Sources

1. Aanes, M.M., Hetland, J., Pallesen, S., Mittelmark, M. B. Does loneliness mediate the stress-sleep quality relation? The Hordaland Health Study. Int. Psychogeriatr, 2011, 22, p. 1-9. [Epub ahead of print]

2. Bartels, M., Cacioppo, J., Hudziak, J. J., Boomsma, D.I. Genetic and environmental contributions to stability in loneliness throughout childhood. Am. J. Med. Gen.: Neuropsychiatric. genetics 2008, 147B(3), p. 385-391.

3. Cacioppo, J., Patric, W. Loneliness: human nature and the need for social connection. New York: W.W. Norton & Co., 2008.

4. Cacioppo, J.T., Hawkley, L.C., Crawford, L.E. et al. Loneliness and health: potential mechanisms. Psychosom. Med. 2002, 64, p. 407-417.

5. Caspi, A., Sugden, K., Moffitt, T., E. et al. Influence of life stress on depression: moderation by a polymorphism in the 5-HTT gene. Science 2003, 301, p. 386-389.

6. Cole, S.W., Mendoza, S.P., Capitanio, J.P. Social stress desensitizes lymphocytes to regulation by endogenous glucocorticoids: insights from in vivo cell trafficking dynamics in rhesus macaques. Psychosom. Med. 2009, 71(6), p. 591-597.

7. Doane, L.D., Adam, E.K. Loneliness and cortisol: momentary, day-to-day, and trait associations. Psychoneuroendocrinology 2010, 35(3), p. 430–441.

8. Dóci I., Hosák, L., Kovářová, M. Osamělost starých lidí jako sociální medicínský problém. Čas. Lék. čes. 2003, 142, s. 505-507.

9. Fragoso, C.A. V., Gill, T.M. Sleep complaints in community-living older persons: A multifactorial geriatric syndrome. J. Am. Geriatr. Soc. 2007, 55(11), p. 1853–1866.

10. Hawkley, L.C., Thisted, R.A., Masi, C.M., Cacioppo, J.T. Loneliness predicts increased blood pressure: 5-year cross-lagged analyses in middle-aged and older adults. Psychol. Aging 2010, 25(1), p. 132-141.

11. Hermesa, G.L., Delgado, B., Tretiakova, M. et al. Social isolation dysregulates endocrine and behavioral stress while increasing malignit burden of spontaneous mammary tumors. Proc. Natl. Acad. Sci. USA 2009, 106(52), p. 22393-22398.

12. Heinrich, L.M., Gullone, E. The clinical significance of loneliness: a literature review. Clin. Psychol. Rev. 2006, 26, p. 695-718.

13. Honzák, R., Seifert, B. Úzkostný pacient s kardiovaskulárními příznaky. Prakt. Lék. 2005. 85(2), s. 102-106.

14. Kuzelova, H., Ptacek, R., Macek, M. Jr. The serotonin transporter gene (5-HTT) variant and psychiatric disorders. Neuroendocrino.l Lett. 2010, 31(1), p. 4-10.

15. Kuželová, H., Ptáček, R., Macek, M. Jr. Polymorfismus genu pro serotoninový transportér 5-HTT v etiologii psychiatrických onemocnění. Čes. slov. Psych. 2010, 106(2), p. 98-104.

16. Nausheen, B., Gidron, Y., Gregg, A. et al. Loneliness, social support and cardiovascular reactivity to laboratory stress. Stress 2007, 10(1), p.  37-44.

17. Peichlová, J., Pavlata, M. Deprese a kardiovaskulární onemocnění. Prakt. Lék. 2002, 7, s. 385-388.

18. Segrin, C., Domschke, T. Social support, loneliness, recuperative processes, and their direct and indirect effects on health. Health Commun. 2011, 26(3), p. 221-232.

19. Smith, S.S., Kozak, N., Sullivan, K.A. An investigation of the relationship between subjective sleep quality, loneliness and mood in an Australian sample: Can daily routine explain the links? Int. J. Soc. Psychiatry. Published online before print November 24, 2010, doi: 10.1177/0020764010387551.

20. Steptoe, A., Owen, N., Kunz-Ebrecht, S.R., Brydon, L. Loneliness and neuroendocrine, cardiovascular, and inflammatory stress responses in middle-aged men and women. Psychoneuroendocrinology 2004, 29(5), p. 593-611.

21. Thurston, R.C., Kubzansky, L.D. Women, loneliness, and incident coronary heart disease. Psychosom. Med. 2009, 71(8), p. 836-842.

22. van Roekel, E., Scholte, R.H., Verhagen, M. et al. Loneliness in adolescence: gene x environment interactions involving the serotonin transporter gene. J. Child. Psychol. Psychiatry 2010, 51(7), p. 747-754.

23. Wilson, R.S., Krueger, K.R., Arnold, S.E. et al. Loneliness and risk of Alzheimer disease. Arch. Gen. Psychiatry 2007, 64, p. 234–240.

Labels
General practitioner for children and adolescents General practitioner for adults
Login
Forgotten password

Enter the email address that you registered with. We will send you instructions on how to set a new password.

Login

Don‘t have an account?  Create new account

#ADS_BOTTOM_SCRIPTS#