Unusual cause of pathologic fracture of a 18-year-old girl


Authors: M. Fabianová 1;  P. Bician 2;  S. Bieliková 1;  K. Hálová 1;  J. Novotný 3;  J. Menšíková 4;  I. Mikšíková 5
Authors‘ workplace: 2. Detská klinika SZU DFNsP, Banská Bystrica, prednosta prof. MUDr. K. Kralinský, PhD. 1;  Klinika pediatrickej hematológie a onkológie SZU DFNsP, Banská Bystrica, prednosta h. doc. MUDr. E. Bubanská, PhD. 2;  Klinika detskej chirurgie SZU DFNsP, Banská Bystrica, prednosta prof. MUDr. M. Vidiščák, PhD., FEBPS 3;  Martinské bioptické centrum, s. r. o., Banská Bystrica, vedúci prof. MUDr. L. Plank, CSc. 4;  Inštitút nukleárnej a molekulárnej medicíny, Banská Bystrica, riaditeľ MUDr. I. Marin 5
Published in: Čes-slov Pediat 2012; 67 (2): 98-102.
Category: Case Report

Overview

Authors present the case of a 18-year-old girl , who was diagnosed with extremely vast bone changes, manifested by a pathologic fracture of the right femur.

These bone changes were caused by a long-term untreated primary hyperparathyreosis resulting from a seldom case of tumor – the parathyroid carcinoma and lead to the formation of a rare brown tumor in paranasal sinuses.

Key words:
hypercalcaemia, primary hyperparathyreosis, parathyroid carcinoma


Sources

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3. Fiedler AG, Rossi C, Gingalewski CA. Parathyroid carcinoma in a child: an unusual case of an ectopically located malignant parathyroid gland with tumor invading the thymus. J Pediatr Surg 2009; 44 (8): 1649–1652.

4. Shane E. Clinical review 122: Parathyroid carcinoma. J Clin Endocrinol Metab 2001; 86: 485–493.

5. Kentoš P, a kol. Metastázujúci karcinóm prištítneho telieska – zriedkavá príčina primárnej hyperparatyreózy. Onkológia (Bratisl.) 2008; 3 (5): 341–344.

6. Mendoza V, Hernandez AF, Marquez MI. Primary hyperthyroidism due to parathyroid carcinoma. Arch Med Res 1997; 28 (2): 303–306.

7. Martinez-Gavidia EM, Bagan JV, Milian-Massanet MA, Lloria de Miguel E, Perez-Valles A. Highly aggresive brown tumor of the maxilla as first manifestation of primary hyperparathyroidism. Int J Oral Maxillofac Surg 2000; 29: 447–449.

8. McCance DR, Kenny BD, Sloan JM, Russell CF, Hadden DR. Parathyroid carcinoma: a review. J R Soc Med 1987; 80 (8): 505–509.

Labels
Neonatology Paediatrics General practitioner for children and adolescents
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