Unusual cause of pathologic fracture of a 18-year-old girl
Authors:
M. Fabianová 1; P. Bician 2; S. Bieliková 1; K. Hálová 1; J. Novotný 3; J. Menšíková 4; I. Mikšíková 5
Authors‘ workplace:
2. Detská klinika SZU DFNsP, Banská Bystrica, prednosta prof. MUDr. K. Kralinský, PhD.
1; Klinika pediatrickej hematológie a onkológie SZU DFNsP, Banská Bystrica, prednosta h. doc. MUDr. E. Bubanská, PhD.
2; Klinika detskej chirurgie SZU DFNsP, Banská Bystrica, prednosta prof. MUDr. M. Vidiščák, PhD., FEBPS
3; Martinské bioptické centrum, s. r. o., Banská Bystrica, vedúci prof. MUDr. L. Plank, CSc.
4; Inštitút nukleárnej a molekulárnej medicíny, Banská Bystrica, riaditeľ MUDr. I. Marin
5
Published in:
Čes-slov Pediat 2012; 67 (2): 98-102.
Category:
Case Report
Overview
Authors present the case of a 18-year-old girl , who was diagnosed with extremely vast bone changes, manifested by a pathologic fracture of the right femur.
These bone changes were caused by a long-term untreated primary hyperparathyreosis resulting from a seldom case of tumor – the parathyroid carcinoma and lead to the formation of a rare brown tumor in paranasal sinuses.
Key words:
hypercalcaemia, primary hyperparathyreosis, parathyroid carcinoma
Sources
1. Kollars J, Zarroug AE, Heerden J, et al. Primary hyperparathyreoidism in pediatric patients. Pediatrics 2005; 115: 974–980.
2. Mittendorf EA, McHenry CR. Parathyroid carcinoma. J Surg Oncol 2005; 89 (3): 136–142.
3. Fiedler AG, Rossi C, Gingalewski CA. Parathyroid carcinoma in a child: an unusual case of an ectopically located malignant parathyroid gland with tumor invading the thymus. J Pediatr Surg 2009; 44 (8): 1649–1652.
4. Shane E. Clinical review 122: Parathyroid carcinoma. J Clin Endocrinol Metab 2001; 86: 485–493.
5. Kentoš P, a kol. Metastázujúci karcinóm prištítneho telieska – zriedkavá príčina primárnej hyperparatyreózy. Onkológia (Bratisl.) 2008; 3 (5): 341–344.
6. Mendoza V, Hernandez AF, Marquez MI. Primary hyperthyroidism due to parathyroid carcinoma. Arch Med Res 1997; 28 (2): 303–306.
7. Martinez-Gavidia EM, Bagan JV, Milian-Massanet MA, Lloria de Miguel E, Perez-Valles A. Highly aggresive brown tumor of the maxilla as first manifestation of primary hyperparathyroidism. Int J Oral Maxillofac Surg 2000; 29: 447–449.
8. McCance DR, Kenny BD, Sloan JM, Russell CF, Hadden DR. Parathyroid carcinoma: a review. J R Soc Med 1987; 80 (8): 505–509.
Labels
Neonatology Paediatrics General practitioner for children and adolescentsArticle was published in
Czech-Slovak Pediatrics
2012 Issue 2
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