Authors: P. Doležalová; P. Telekešová; D. Němcová; J. Hoza Authors‘ workplace: Klinika dětského a dorostového lékařství 1. LF UK, Praha Published in: Čes. Revmatol., , 2001, No. 2, p. 78-84. Category:
The study objectives were twofold: 1. To develop a method of direct nailfold capillaroscopy (NFC)applicable to a wide range of paediatric patients. 2. To analyze capillaroscopy images in a representative group of healthy children and rheumatology patients using this method. We examined 157healthy children aged 7 months to 17 years and 46 children with various diseases: juvenile idiopathicarthritis (JIA: 18), diffuse connective tissue diseases (CTD: 10), systemic lupus erythematosus (SLE:5), primary vasculitis (Henoch-Schönlein purpura, HSP: 9, other types of vasculitis, VAS: 6) andRaynaud’s disease (RS: 3). A stereomicroscope with fibreoptic illumination was used. The followingparameters were analysed in the end capillary row: linear density, tortuosity, abnormal loops,avascularity and disarrangement. The mean linear density in healthy children ranged from 7.3 – 8.7cap/mm, the tortuosity was 20 – 60 % (grade 0.8 – 1.4). In healthy children abnormal capillaries aswell as avascularity were present extremely rarely, the degree of disarrangement was also lowranging from 0.7 – 1.4 in a 4-point scale. Children under 4 years of age had lower capillary countsand a higher tortuosity as well as disarrangement degree (p
Key words: nailfold capillaroscopy, children, microangiopathy
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