Secondary Amyloidosis in a Patient with Gouty Arthritis

Authors: A. Pavelková;  J. Gatterová;  M. Merta 1;  Stejskalová;  . 2;  Z. Vernerová 2;  K. Pavelka
Authors‘ workplace: Revmatologický ústav, Praha 1 I. interní klinika 1. LF, VFN, Praha 2 I. patologicko-anatomický ústav 1. LF UK, Praha
Published in: Čes. Revmatol., , 2000, No. 2, p. 72-75.


The authors describe the case of a 45-year-old man with a four-year history of chronic tophaceousgout. The patient suffered from proteinuria and chronic renal failure, and from renal biopsy AAamyloidosis was diagnosed. With regard to the finding of paraprotein (IgGk) in serum, a myelomawas suspected but was not confirmed and therefore it was concluded that benign monoclonalgammapathy (MGUS) is involved. The occurrence of AA amyloidosis in gout is rare and so far onlya few cases were described. In the mentioned patient it will be however necessary to follow up thepossible development of MGUS and potential relations to AA amyloidosis.

Key words:
gout, amyloidosis, benign monoclonal gammapathy

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Dermatology & STDs Paediatric rheumatology Rheumatology
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