Pilot project FLS OSTEO – Secondary prevention of osteoporotic fractures in persons aged over 50 in the Czech Republic

Authors: Němec Pavel 1,2;  Pikner Richard 3,4,7,8;  Hejduk Karel 1,2;  Ngo Ondřej 1,2;  Budíková Barbora 1;  Šanca Ondřej 1;  Palička Vladimír 4,5;  Rosa Jan 4,6;  Jarkovský Jiří 1,2;  Májek Ondřej 1,2
Authors‘ workplace: Ústav zdravotnických informací a statistiky České republiky, Národní screeningové centrum, Praha 1;  Institut biostatistiky a analýz LF MU, Brno 2;  Oddělení klinických laboratoří a kostního metabolizmu, Klatovská nemocnice, a. s., Klatovy 3;  Společnost pro metabolické onemocnění skeletu, ČLS JEP, z. s. 4;  Osteocentrum, Ústav klinické biochemie a diagnostiky LF UK a FN Hradec Králové 5;  Affidea Praha, s. r. o. 6;  Ústav klinické biochemie a hematologie LF UK a FN Plzeň 7;  Katedra záchranářství, diagnostických oborů a veřejného zdravotnictví, Fakulta zdravotnických studií, Západočeská, Univerzita v Plzni 8
Published in: Clinical Osteology 2021; 26(3): 133-142


Every third female and every fifth male over 50 years of age suffer from osteoporotic fracture. Approximately 15,000 patients with hip fracture in the Czech Republic are hospitalized every year, and nearly 25 % of them die within one year of the complications associated with this injury. Additionally, initial osteoporotic fracture increases the risk of another subsequent fracture by 2–5fold. Under-diagnosis of osteoporosis in the population is one of the most serious problems in the Czech Republic, which is related not only to the lack of information about the problem itself in the target population but also to the absence of a comprehensive program of secondary prevention of osteoporotic fractures in the Czech Republic. The ongoing national, prospective, multicenter pilot project entitled OSTEO – Secondary prevention of osteoporotic fractures in persons aged over 50 who have had their first osteoporotic fracture organized by the National Screening Centre of Institute of Health Information and Statistics of the Czech Republic aims to improve this situation. The pilot project is based on the FLS (Fraction Liaison Services) system, i.e. a coordinated search for patients with osteoporosis after a fracture, which allows to perform their subsequent differential diagnostics at the osteological centers and, if necessary, to initiate adequate treatment. The global objective of the pilot project is to verify the feasibility of implementing the FLS system in the Czech healthcare environment and to design a population-wide program for the prevention of secondary osteoporotic fractures in the Czech Republic based on this approach to ensure maximum positive impact on population health and high cost-effectiveness of the intervention.


Bone fracture – FLS – osteoporosis – pilot project – secondary prevention

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Clinical biochemistry Paediatric gynaecology Paediatric radiology Paediatric rheumatology Endocrinology Gynaecology and obstetrics Internal medicine Orthopaedics General practitioner for adults Radiodiagnostics Rehabilitation Rheumatology Traumatology
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