Fibrous dysplasia


Authors: Raška Ivan
Authors‘ workplace: III. interní klinika – endokrinologie a metabolismu 1. LF UK a VFN v Praze
Published in: Clinical Osteology 2021; 26(3): 143-146
Category:

Overview

Fibrous dysplasia (FD) is a congenital skeletal disease characterized by the presence of bone lesions containing fibrous connective tissue. FD occurs in monoostotic or polyostotic form. Rarely, fibrous dysplasia is part of McCune-Albright syndrome together with “café au lait” cutaneous hyperpigmentations and endocrine hyperfunction (especially pubertas praecox, thyrotoxicosis, Cushing’s syndrome, etc.). Clinical symptomatology depends on the extent of the bone disease. Most bone lesions in FD are asymptomatic, with a minority of bone lesions manifesting as pain, bone deformity, or pathological fracture. The following article provides a brief overview of current knowledge about fibrous dysplasia.

Keywords:

bone deformity – fibrous dysplasia – McCune-Albright syndrome – pathological fracture


Sources
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Clinical biochemistry Paediatric gynaecology Paediatric radiology Paediatric rheumatology Endocrinology Gynaecology and obstetrics Internal medicine Orthopaedics General practitioner for adults Radiodiagnostics Rehabilitation Rheumatology Traumatology
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